64441-70-9

Upstream product

• 67-56-1 methanol 
• 84-66-2 Diethyl phthalate 
• 85-44-9 phthalic anhydride 
• 115-10-6 Dimethyl ether 
• 71-43-2 benzene 
• 3199-08-4 1,1,3,3-tetrachloro-1,3-dihydroisobenzofuran 
• 109501-53-3 (+/-)-(2ar,6ac)-2a,3,6,6a-tetrahydro-2H-spiro[3t,6t-etheno-cyclobutabenzene-1,2'-[1,3]dioxolane]-4,5-dicarboxylic acid dimethyl ester 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 124-41-4 sodium methylate 
• 88-95-9 Phthaloyl dichloride 
• 59006-02-9 di-silver phthalate 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 93-58-3 benzoic acid methyl ester 

Downstream Products

• 113710-82-0 2-[2-(1-hydroxy-1-methylethyl)phenyl]-2-propanol 
• 104175-19-1 1-[2-(α-hydroxy-isopropyl)-phenyl]-ethanone 
• 6134-98-1 2-(Β-methylcrotonyl)-idandion-1,3 
• 101587-00-2 N¹,N²-bis[2-(vinyloxy)ethyl]phthalamide 
• 52679-57-9 2-(3-phenyl-propionyl)-indan-1,3-dione 
• 3216-03-3 10,10-Diphenyl-10H-anthracen-9-one 
• 62761-89-1 HOC(Ph)2C₆H₄-2-(COPh) 
• 6175-42-4 2-butyryl-1H-indene-1,3(2H)-dione 
• 6538-32-5 [2-[hydroxy(diphenyl)methyl]phenyl]diphenylmethanol 
• 34708-78-6 2-(cyclohexanecarbonyl)-1H-indene-1,3(2H)-dione 
• 1785-95-1 2-benzoyl-1,3-indanedione 
• 38228-99-8 N,N'-dibenzylphthalamide 
• 3052-65-1 α.ω-Methacryl-bis-(diethylenglykol phthalat) 
• 2387-65-7 di(triethylene glycol)phthalate dimethacrylate 

Relevant academic research and scientific papers

Nickel-Catalyzed Carboxylation of Aryl C?F Bonds with CO2

The C?F bond is the strongest single bond and it is one of the most challenging tasks to achieve the C?F bond functionalization. Here, we describe the first nickel-catalyzed selective defluorinative carboxylation of aryl C?F bonds with CO2. Var

Electrochemical esterification via oxidative coupling of aldehydes and alcohols

An electrolytic method for the direct oxidative coupling of aldehydes with alcohols to produce esters is described. Our method involves anodic oxidation in presence of TBAF as supporting electrolyte in an undivided electrochemical cell equipped with graphite electrodes. This method successfully couples a wide range of alcohols to benzaldehydes with yields ranging from 70 to 90%. The protocol is easy to perform at a constant voltage conditions and offers a sustainable alternative over conventional methods.

Method for coproducing methyl benzoic acid Process for the production of methyl benzoates and diesters of phthalic acids

The invention discloses a coproduction method of methylbenzoic acid, methyl benzoate and benzenedicarboxylic acid diester. The method comprises the following steps: (1) continuously introducing xylene, a catalyst and oxygen-containing gas into an oxidation reactor for a reaction, and controlling oxygenic concentration in the tail gas to not exceed 5% by controlling introduction amount of the oxygen-containing gas to obtain an oxidation reaction liquid; (2) feeding the obtained oxidation reaction liquid into a predistillation tower for distillation separation to obtain a low-boiling-point component and a predistillation tower bottom liquid; (3) feeding the predistillation tower bottom liquid into a distillation tower for distillation to obtain a methylbenzoic acid product and a distillationtower bottom liquid; (4) mixing the distillation tower bottom liquid and alcohol for an esterification reaction, and controlling the reaction endpoint to be lower than 0.5wt% of the content of methylbenzoic acid to obtain an esterification reaction liquid; (5) performing distillation separation on the obtained esterification reaction liquid to obtain methyl benzoate and benzenedicarboxylic acid diester products. The method has the advantages that the process is simple, equipment investment is low, and the method is environmentally friendly and has good comprehensive economic benefits.

Ultralow-Molecular-Weight Stimuli-Responsive and Multifunctional Supramolecular Gels Based on Monomers and Trimers of Hydrazides

The simpler, the better. A series of simple, neutral and ultralow-molecular-weight (MW: 140–200) hydrazide-derived supramolecular gelators have been designed and synthesized in two straightforward steps. For non-conjugated cyclohexane-derived hydrazides, their monomers can self-assemble to form gels through intermolecular hydrogen bonds and dipole-dipole interactions. Significantly, conjugated phthalhydrazide can self-aggregate into planar and circular trimers through intermolecular hydrogen bonds and then self-assemble to form gels through intermolecular π–π stacking interactions. It is interesting that these simple gelators exhibit unusual properties, such as self-healing, multi-response fluorescence, and visual and selective recognition of chiral (R)/(S)-1,1′-binaphthalene-2,2′-diamine and S2? through much different times of gel re-formation and blue-green color change, respectively. These results underline the importance of supramolecular gels and extend the scope of supramolecular gelators.

Cobalt Nanoparticles-Catalyzed Widely Applicable Successive C?C Bond Cleavage in Alcohols to Access Esters

Selective cleavage and functionalization of C?C bonds have important applications in organic synthesis and biomass utilization. However, functionalization of C?C bonds by controlled cleavage remains difficult and challenging because they are inert. Herein, we describe an unprecedented efficient protocol for the breaking of successive C?C bonds in alcohols to form esters with one or multiple carbon atoms less using heterogeneous cobalt nanoparticles as catalyst with dioxygen as the oxidant. A wide range of alcohols including inactive long-chain alkyl aryl alcohols undergo smoothly successive cleavage of adjacent ?(C?C)n? bonds to afford the corresponding esters. The catalyst was used for seven times without any decrease in activity. Characterization and control experiments disclose that cobalt nanoparticles are responsible for the successive cleavage of C?C bonds to achieve excellent catalytic activity, while the presence of Co-Nx has just the opposite effect. Preliminary mechanistic studies reveal that a tandem sequence reaction is involved in this process.

Regioselective arene homologation through rhenium-catalyzed deoxygenative aromatization of 7-oxabicyclo[2.2.1]hepta-2,5-dienes

Combined use of oxorhenium catalysts with triphenyl phosphite as an oxygen acceptor allowed efficient deoxygenative aromatization of oxabicyclic dienes. The reaction proceeded under neutral conditions and was compatible with various functional groups. Combining this deoxygenation with regioselective bromination and trapping of the generated aryne with furan resulted in benzannulative π-extension at the periphery of the PAHs. This enabled direct use of unfunctionalized PAHs for extension of π-conjugation. Iteration of the transformations increased the number of fused-benzene rings one at a time, which has the potential to alter the properties of PAHs by fine-tuning the degree of π-conjugation, shape, and edge topology.

Efficient and Recyclable RuCl3 ? 3H2O Catalyst Modified with Ionic Diphosphine for the Alkoxycarbonylation of Aryl Halides

A series of ionic (mono-/di-)phosphines (L2, L4, and L6) with structural similarity and their corresponding neutral counterparts (L1, L3, and L5) were applied to modulate the catalytic performance of RuCl3 ? 3H2O. With the involvement of the ionic diphosphine (L4), in which the two phosphino-fragments were linked by butylene group, RuCl3 ? 3H2O with advantages of low cost, robustness, and good availability was found to be an efficient and recyclable catalyst for the alkoxycarbonylation of aryl halides. The L4-based RuCl3 ? 3H2O system corresponded to the best conversion of PhI (96 %) along with 99 % selectivity to the target product of methyl benzoate as well as the good generality to alkoxycarbonylation of different aryl halides (ArX, X=I and Br) with alcohols MeOH, EtOH, i-PrOH and n-BuOH. The electronic and steric effects of the applied phosphines, which were analyzed by the 31P NMR for 1J31P-77Se1J measurement and single-crystal X-ray diffraction, were carefully co-related to the performance RuCl3 ? 3H2O catalyst. In addition, the L4-based RuCl3 ? 3H2O system could be recycled successfully for at least eight runs in the ionic liquid [Bmim]PF6.

Diacidic ionic liquid supported on magnetic-silica nanocomposite: a novel, stable, and reusable catalyst for selective diester production

Abstract: Supported diacidic ionic liquid on magnetic silica nanoparticles (SDAIL@magnetic nanoSiO2) was successfully prepared through a multi-step approach. 2,2- bis ((3- methylimidazolidin-1-yl) methyl) propane- 1,3- diol bromide salt was immobilized onto the surface of magnetic silica nanoparticles via covalent bonding to prepare a novel powerful acidic catalyst. The synthesized catalyst was characterized by FT-IR, SEM, TGA, VSM, N2 adsorption–desorption measurements and acid-base titration. The catalytic activity of the prepared SDAIL@magnetic nanoSiO2 was investigated for the selective diesterification of alcohols by phthalic anhydride to afford corresponding dialkyl plasticizers under solvent-free conditions. The nature of two acidic counter anions as well as the presence of Lewis acidic species (Fe3O4) on the magnetic nanosilica and high surface area of the nanosilica influenced the behavior of the catalyst. Surperisingly, the high acidic character of the catalyst facilitates the reaction with a short reaction time. Furthermore, TG analysis strongly demonstrates that major content of IL is still stable on the support up to 290?°C, so catalyst has a good thermal stability. Under the optimized conditions, the conversion of phthalic anhydride was 100% and diester plasticizers were obtained with excellent yields (80–100%). The SDAIL@magnetic nanoSiO2 catalyst showed a good reusability and could be easily separated from the reaction mixture using an external magnet thanks to its superparamagnetic behavior and reused for several runs without significant activity loss. An important advantage of the SDAIL@magnetic nanoSiO2 was its high-hydrophilicity resulted in excellent selectivity towards the formation of only diesters which are commonly used plasticizers in different industries. Graphical abstract [Figure not available: see fulltext.].

A novel hydrogen-bonded silica-supported acidic ionic liquid: An efficient, recyclable and selective heterogeneous catalyst for the synthesis of diesters

Abstract: In this study, two novel acidic ionic liquids, including a hydroxyl functionalized diacidic ionic liquid [HFDAIL] and a sulfonated diacidic ionic liquid [SFDAIL], were prepared and immobilized on the surface of silica nanoparticles (SNPs) via hydrogen bonding. The materials were characterized by FT-IR, NMR, SEM, nitrogen physisorption measurement, TGA and acid-base titration. The catalytic activity of the prepared catalysts was investigated in the synthesis of phthalate, maleate and succinate diesters under solvent-free conditions. It was found that nanosilica@[HFDAIL] with higher availability of acidic sites and higher hydrophilicity was more efficient compared to the nanosilica@[SFDAIL]. Notably, nanosilica@[HFDAIL] catalyst has also demonstrated excellent selectivity for the diester product while the monoester product was predominant in the case of nanosilica@[SFDAIL] even after prolonged reaction time or higher catalyst loading. In addition, the nanosilica@[HFDAIL] catalyst could be separated by simple filtration and reused several times without any significant loss of catalytic performance, but a remarkable decrease in activity was observed for nanosilica@[SFDAIL] in the next runs. GRAPHICAL ABSTRACT?: SYNOPSIS Two novel acidic ionic liquids, including a hydroxyl functionalized diacidic ionic liquid [HFDAIL] and a sulfonated diacidic ionic liquid [SFDAIL], were prepared and immobilized on the surface of silica nanoparticles via hydrogen bonding. The catalytic activity of the catalysts was investigated in the synthesis of diesters under solvent-free conditions.

Silica supported polynuclear sulfonate acidic ionic liquid and application

The invention relates to silica supported polynuclear sulfonate acidic ionic liquid and a method for preparing dimethyl phthalate by utilizing the silica supported polynuclear sulfonate acidic ionic liquid. The silica supported polynuclear sulfonate acidic ionic liquid is prepared by performing silica supporting on polynuclear sulfonate acidic ionic liquid shown in a formula (I). According to thecatalyst in the invention, the problems existing in the conventional acid catalyst that follow-up treatment is complicated, equipment corrosion is severe, lots of industrial wastewater is discharged and the like can be solved. Moreover, the catalyst has excellent heat-resistant stability and high-efficiency catalytic activity (an esterification rate can reach 96-99%) in a reaction of preparing thedimethyl phthalate, is easily separated from the product, can be repeatedly used, and is simple in recovery operation, long in life and mild in reaction conditions, pollution of the acid catalyst tothe environment and corrosion of the catalyst on equipment can be overcome, the production process is simplified, and the production cost is saved. The structural formula is as shown in the description.