647852-19-5

Basic information

• Product Name: (S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyric acid methyl ester
• Synonyms: (S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyric acid methyl ester
• CAS NO: 647852-19-5
• Molecular Weight: 449.549
• Mol File: 647852-19-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyric acid methyl ester(647852-19-5)
• EPA Substance Registry System: (S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyric acid methyl ester(647852-19-5)

Safety Data

• Hazardous Substances Data: 647852-19-5(Hazardous Substances Data)

Upstream product

• 647852-04-8 [(S)-2-Oxo-4-phenyl-3-(trityl-amino)-butyl]-phosphonic acid dimethyl ester 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 63-91-2 L-phenylalanine 

Downstream Products

• 647852-26-4 methyl (2S,3S)-3-(benzamido)-2-hydroxy-4-phenylbutanoate 
• 257296-68-7 methyl (4S,trans)-4,5-dihydro-2-benzyl-4-phenyl-5-carboxylate 
• 246523-10-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-4-phenylbutanoate 
• 145902-33-6 (S)-3-Amino-2-oxo-4-phenyl-butyric acid methyl ester; hydrochloride 

Relevant articles and documents

A practical diastereoselective synthesis of β-amino-α-hydroxy carboxylates

Practical synthetic routes to β-amino-α-hydroxy carboxylates (AHC) have been developed from amino acids. Reduction of β-amino-α- keto esters 6 with NaBH4 was found to give anti-AHCs 7 in high de, which were efficiently converted to the corresponding syn-AHCs 8 via oxazolidine ring 10 formation.