6483-99-4

Basic information

• Product Name: 4(1H)-Quinazolinethione, 2-phenyl-
• CAS NO: 6483-99-4
• Molecular Formula: C14H10N2S
• Molecular Weight: 238.313
• Mol File: 6483-99-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinethione, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinethione, 2-phenyl-(6483-99-4)
• EPA Substance Registry System: 4(1H)-Quinazolinethione, 2-phenyl-(6483-99-4)

Safety Data

• Hazardous Substances Data: 6483-99-4(Hazardous Substances Data)

Upstream product

• 396716-35-1 2-phenyl-4-iminobenzo[d][1,3]thiazine 
• 6484-25-9 4-chloro-2-phenylquinazoline 
• 59525-06-3 2-benzoylaminothiobenzamide 
• 100-52-7 benzaldehyde 
• 121998-76-3 2-phenyl-2,3-dihydro-4(1H)-quinazolinone 
• 28144-70-9 anthranilic acid amide 
• 2454-39-9 2-aminobenzothioamide 
• 98-88-4 benzoyl chloride 
• 100698-06-4 2-mercapto-2-thioxo-2,3-dihydro-1H-2λ⁵-benzo[1,3,2]diazaphosphinine-4-thione pyridinium salt 
• 40288-69-5 N-(2-cyanophenyl)benzamide 
• 15437-26-0 N-(2-cyanophenyl)benzimidoyl chloride 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 

Downstream Products

• 6484-29-3 2-phenyl-4-quinazolinylhydrazine 
• 13193-72-1 2,2'-diphenyl-4,4'-disulfanediyl-bis-quinazoline 
• 145471-16-5 C₁₅H₁₀N₄O 
• 145470-99-1 C₁₆H₁₂N₄ 
• 6484-29-3 C₁₄H₁₂N₄ 
• 6506-59-8 5-phenyl-1,2,4-triazolo<4,3-c>quinazoline 
• 6499-41-8 5-phenyltetrazolo<1,5-c>quinazoline 
• 896725-99-8 4-(2,4-dimethoxybenzylsulfanyl)-2-phenylquinazoline 
• 115765-12-3 2,3-dihydro-2,5-diphenyl-3-(phenylimino)-striazolo<4,3-c>quinazoline 
• 115765-16-7 6-phenyl-4-anilino-2H-s-triazino<1,2-c>-quinazolin-2-thione 
• 115765-15-6 6-phenyl-4-anilino-2H-s-triazino<1,2-c>-quinazolin-2-one 
• 115765-09-8 3-anilino-5-phenyl-s-triazolo<4,3-c>quinazoline 
• 33399-80-3 3-(bromomethyl)-2,3-dihydro-5-phenylthiazolo<3,2-c>quinazolin-4-ium bromide 
• 105251-22-7 3-(bromomethyl)-5-phenylthiazolo<3,2-c>quinazolin-4-ium bromide 

Relevant articles and documents

Synthesis and Antimicrobial Activity of Methyl 2-(2-(2-Arylquinazolin-4-yl)sulfanyl)acetylamino Alkanoates

A series of methyl 2-(2-(2-arylquinazolin-4-yl)sulfanyl)acetylamino alkanoates have been developed on the basis of the S-chemoselective reaction of 2-arylquinazolin-4(3H)-thione with ethyl chloroacetate and N,N′-dicyclohexylcarbodiimide coupling method with amino acid ester hydrochloride. The precursor 2-arylquinazolin-4(3H)-thione was prepared by a new thiation method from 2-arylquinazolin-4(3H)-one by a two-step reaction that includes chlorination and then the reaction with N-cyclohexyldithiocarbamate cyclohexyl ammonium salt. The antimicrobial activity of the synthesized compounds was tested in vitro via paper-disc agar-plate method against two bacterial strains Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli and a pathogenic yeast Candida albicans. Most synthesized compounds showed remarkable antibacterial activity against E.?coli overpassing the standard reference antibiotics applied: tetracycline, erythromycin, and novobiocin. On the other hand, most synthesized compounds gave moderate antifungal activity against pathogenic yeast C.?albicans.

2-Alkyl(aryl)-quinazolin-4(3 H)-thiones, 2-R-(quinazolin-4(3 H)-ylthio)carboxylic acids and amides: Synthesis, molecular docking, antimicrobial and anticancer properties

In this study, a series of novel 2-alkyl(aryl)-quinazolin-4(3H)-thiones, 2-R-(quinazolin-4(3H)-ylthio)carboxylic acids and amides were synthesized and evaluated for antimicrobial and anticancer activities. Their structure was confirmed by elemental analys

QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY

The present invention relates to novel quinazoline derivatives effective in lowering blood glucose level and body weight, and a medicine for treatment and/or prevention of diabetes and/or obesity, which comprises the compound as an active ingredient.