65105-52-4 Usage
Uses
Strobilurin B is an antifungal agent that acts by inhibiting mitochondrial respiration in fungi. It is also used as a mitochondrial activity inhibitors of cancer-initiating cells.
Definition
ChEBI: An enoate ester that is the methyl ester of (2E,3Z,5E)-6-(4-chloro-3-methoxyphenyl)-2-(methoxymethylene)-3-methylhexa-3,5-dienoic acid.
Check Digit Verification of cas no
The CAS Registry Mumber 65105-52-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,1,0 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 65105-52:
(7*6)+(6*5)+(5*1)+(4*0)+(3*5)+(2*5)+(1*2)=104
104 % 10 = 4
So 65105-52-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H19ClO4/c1-12(14(11-20-2)17(19)22-4)6-5-7-13-8-9-15(18)16(10-13)21-3/h5-11H,1-4H3/b7-5+,12-6-,14-11+
65105-52-4Relevant articles and documents
The total synthesis of strobilurin B
Popovsky,Stepanov,Grigorieva, N. Ya.
, p. 491 - 496 (2015/02/02)
A new regio- and stereocontrolled total synthesis of the antibiotic strobilurin B is performed in nine steps in 5.5% overall yield.
Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin
Coleman, Robert S.,Lu, Xiaoling
, p. 423 - 425 (2008/02/05)
An efficient, six-step stereocontrolled total synthesis of the antifungal agent strobilurin B is reported and was based on a convergent bi-directional coupling featuring a hetero-bis-1,4-metallated pentadiene system as the linchpin. The Royal Society of C