163041-47-2

Usage

Uses

Used in Pharmaceutical Industry:
(Z)-Methyl 2-iodo-3-methoxyacrylate is used as a building block for the production of bioactive molecules, contributing to the development of new pharmaceuticals. Its unique chemical properties and reactivity make it a promising candidate for creating innovative drugs and therapies.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, (Z)-Methyl 2-iodo-3-methoxyacrylate serves as a key intermediate in the synthesis of bioactive compounds, which can be used in the development of pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.
Used in Academic Research:
(Z)-Methyl 2-iodo-3-methoxyacrylate is also employed in academic research settings due to its distinctive chemical characteristics and reactivity. Researchers use (Z)-Methyl 2-iodo-3-Methoxyacrylate to explore new reactions, mechanisms, and potential applications in various fields of chemistry and materials science.
Safety Precautions:
It is crucial to handle (Z)-Methyl 2-iodo-3-methoxyacrylate with care, as it is potentially hazardous. To minimize risks, it should be managed and stored according to the best laboratory practices, ensuring the safety of both the researchers and the environment.

Upstream product

• 5788-17-0 methyl (2E)-3-methoxy-2-propenoate 
• 5199-50-8 methyl 2-iodoacetate 
• 107-31-3 Methyl formate 
• 34846-90-7 methyl 3-methoxyprop-2-enoate 

Downstream Products

• 103455-39-6 methyl (E)-2-(4-chlorophenyl)-3-methoxy-2-propenate 
• 1266105-11-6 (E)-methyl 2-(2-(benzyloxy)-5-bromophenyl)-3-methoxyacrylate 
• 114077-42-8 (E)-3-methoxy-2-(2-hydroxyphenyl)-acrylic acid methyl ester 
• 1266105-08-1 6-(4-(2-cyanophenoxy)-6-(2-((E)-1-(methoxycarbonyl)-2-methoxyvinyl)phenoxy)pyrimidin-2-yl)hexanoic acid 
• 131860-97-4 (E)-methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxy-propenoate 
• 103497-78-5 (E)-3-methoxy-2-(2-benzyloxyphenyl)acrylic acid methyl ester 
• 215934-32-0 azoxystrobin 
• 103455-21-6 methyl (E)-2-phenyl-3-methoxy-2-propenate 
• 163041-49-4 methyl (E)-2-(4-methylphenyl)-3-methoxy-2-propenate 
• 103455-38-5 methyl (E)-2-(2-chlorophenyl)-3-methoxy-2-propenate 

Relevant academic research and scientific papers

MICROBIOCIDAL COMPOUNDS

Compounds of the formula (I), wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.

MICROBIOCIDAL COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.

MICROBIOCIDAL COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.

MICROBIOCIDAL COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.

Dehydration-type Ti-Claisen Condensation (Carbonhomologation) of α-Heteroatom-substituted Acetates with Alkyl Formates: Utilization as (Z)-Stereodefined Cross-coupling Partners and Application to Concise Synthesis of Strobilurin A

TiCl4?Et3N or ?Bu3N reagent conducted a highly (Z)-stereoselective carbon homologation (dehydration type Ti-Claisen condensation) of alkyl α-heteroatom (halo and sulfonyloxy)-substituted acetates (XCH2CO2R) with alkyl formates (HCO2R) to afford various alkyl β-alkoxy-α-halo or sulfonyloxy-substituted acrylates (24 examples; 51%–91% yield). Stereoretentive Suzuki-Miyaura, Negishi, and Sonogashira cross-couplings using the obtained methyl β-methoxy-α-halo or sulfonyloxy-substituted acrylates proceeded smoothly to produce a variety of β-alkoxy-α-substituted acrylates in moderate to high yield (35 examples; 29%–99% yield). As a successful application, a 3-step straightforward synthesis of strobilurin A was performed utilizing the present reaction sequence (dehydration type Ti-Claisen condensation and Suzuki-Miyaura cross-coupling), wherein the geometry of the three consecutive olefins (2E,3Z,5E) was completely maintained. (Figure presented.).

MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME

The present inventions concerns use of a certain methoxyacrylate compound to control mosquitoes, and vector control solutions comprising a defined methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controll

Method for preparing azoxystrobin on basis of Suzuki reaction

The invention relates to a method for preparing azoxystrobin on basis of a Suzuki reaction. The method comprises the following steps: dissolving a mixture composed of methyl (E)-2-[2-(6-chloropyrimidinyl-4-yloxo)phenyl]-3-methoxy acrylate, cesium carbonate and 2-cyanophenol according to a molar ratio of 1:2:2 in a solvent, stirring at 85DEG C under the protection of N2 for 7h, and separating and purifying the obtained mixture to prepare azoxystrobin. The novel green synthesis method provided by the invention has the advantages of low cost, high yield, simple process, and suitableness for mass production.

A concise synthesis of azoxystrobin using a Suzuki cross-coupling reaction

A simple, efficient and eco-friendly process for the synthesis in good yield of azoxystrobin from 2-bromophenol has been developed using phenolic hydroxyl protection, Grignard reaction, Suzuki cross-coupling, hydrogenation and a nucleophilic reaction on a 2-chloropyrimidine.

Total synthesis of hydroxystrobilurin A via Stille coupling

A six-step total synthesis of the fungicidal natural product hydroxystrobilurin A is described, utilising Stille chemistry for efficient access to the strobilurin (E,Z,E)-triene system.

Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin

An efficient, six-step stereocontrolled total synthesis of the antifungal agent strobilurin B is reported and was based on a convergent bi-directional coupling featuring a hetero-bis-1,4-metallated pentadiene system as the linchpin. The Royal Society of C