65109-80-0

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 4-hydroxyphenyl ester
• CAS NO: 65109-80-0
• Molecular Formula: C7H5F3O4S
• Molecular Weight: 242.176
• Mol File: 65109-80-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 4-hydroxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 4-hydroxyphenyl ester(65109-80-0)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 4-hydroxyphenyl ester(65109-80-0)

Safety Data

• Hazardous Substances Data: 65109-80-0(Hazardous Substances Data)

Upstream product

• 421-83-0 trifluoromethane sulfonyl chloride 
• 123-31-9 hydroquinone 
• 1071193-33-3 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 4846-21-3 O-phenylhydroxylamine 
• 65109-75-3 N-(phenoxy)-4-methylbenzenesulfonamide 
• 71-43-2 benzene 
• 64-19-7 acetic acid 
• 1493-13-6 trifluorormethanesulfonic acid 
• 75-89-8 2,2,2-trifluoroethanol 

Downstream Products

• 1073561-83-7 diisopropyl 4-hydroxyphenylphosphonate 

Relevant articles and documents

Gold(I)-Catalyzed Intramolecular Hydroarylation of Phenol-Derived Propiolates and Certain Related Ethers as a Route to Selectively Functionalized Coumarins and 2 H-Chromenes

Methods are reported for the efficient assembly of a series of phenol-derived propiolates, including the parent system 56, and their Au(I)-catalyzed cyclization (intramolecular hydroarylation) to give the corresponding coumarins (e.g., 1). Simple syntheses of natural products such as ayapin (144) and scoparone (145) have been realized by such means, and the first of these subject to single-crystal X-ray analysis. A related process is described for the conversion of propargyl ethers such as 156 into the isomeric 2H-chromene precocene I (159), a naturally occurring inhibitor of juvenile hormone biosynthesis.

HF-Pyridine: A versatile promoter for monoacylation/sulfonylation of phenolic diols and for direct conversion of t-butyldimethylsilyl ethers to the corresponding acetates

Monoacylation and trifluoromethanesulfonylation of phenolic diols were achieved by the aid of HF-pyridine, whereas diacylation occurred with pyridine alone. Furthermore, HF-pyridine was found to promote the direct conversion of t-butyldimethylsilyl ethers to the corresponding acetates.

Acid-Catalyzed Solvolysis of N-Sulfonyl- and N-Acyl-O-arylhydroxylamines. Phenoxenium Ions

The acid-catalyzed reaction of N-acyl- and N-sulfonyl-O-arylhydroxylamines with benzene proceeded quite smoothly to give 2- and 4-hydroxybiphenyls.The results of product analysis, the orientation of the reaction, and the effects of substituents on the nitrogen atom and on the phenyl ring suggested a mechanism that involves a phenoxenium ion.The phenoxenium ion was trapped by benzene and other various nucleophiles.