65130-79-2

Basic information

• Product Name: bis(2-chlorobenzyl)amine
• Synonyms: bis(2-chlorobenzyl)amine
• CAS NO: 65130-79-2
• Molecular Weight: 266.17
• Mol File: 65130-79-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: bis(2-chlorobenzyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-chlorobenzyl)amine(65130-79-2)
• EPA Substance Registry System: bis(2-chlorobenzyl)amine(65130-79-2)

Safety Data

• Hazardous Substances Data: 65130-79-2(Hazardous Substances Data)

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 89-98-5 2-chloro-benzaldehyde 
• 89-97-4 2-CHLOROBENZYLAMINE 
• 1498-93-7 N,N'-Bis<2-chlorobenzylidene>-2-chlorophenylmethanediamine 
• 64-17-5 ethanol 
• 3717-26-8 (E)-2-chlorobenzaldehyde oxime 
• 64-19-7 acetic acid 
• 609-66-5 2-chlorobenzamide 

Downstream Products

• 152389-21-4 N-(2-chlorobenzylidene)-1-(2-chlorophenyl)methylamine 

Relevant articles and documents

Switching Selectivity in Copper-Catalyzed Transfer Hydrogenation of Nitriles to Primary Amine-Boranes and Secondary Amines under Mild Conditions

A simple and efficient copper-catalyzed selective transfer hydrogenation of nitriles to primary amine-boranes and secondary amines with an oxazaborolidine-BH3 complex is reported. The selectivity control was achieved under mild conditions by switching the solvent and the copper catalysts. More than 30 primary amine-boranes and 40 secondary amines were synthesized via this strategy in high selectivity and yields of up to 95%. The strategy was applied to the synthesis of 15N labeled in 89% yield.

Selective Synthesis of Secondary Amines from Nitriles by a User-Friendly Cobalt Catalyst

Selective hydrogenation/reductive amination of nitriles to secondary amines catalyzed by an inexpensive and user-friendly cobalt complex, (Xantphos)CoCl2, is reported. The use of (Xantphos)CoCl2 and ammonia borane (NH3?BH3) combination affords the selective reduction of nitriles to symmetrical secondary amines, whereas the employment of (Xantphos)CoCl2 and dimethylamine borane (Me2NH?BH3) along with external amines produce unsymmetrical secondary amines and tertiary amines. The general applicability of this methodology is demonstrated by the synthesis of 43 symmetrical and unsymmetrical secondary and tertiary amines bearing diverse functionalities. (Figure presented.).

Cobalt complex, preparation method thereof, and application thereof in selective catalysis of transfer hydrogenation reaction of cyano group

The invention discloses a cobalt complex, a preparation method thereof, and an application thereof in the selective catalysis of a transfer hydrogenation reaction of a cyano group. The structural formula of the cobalt complex is represented by formula I. The cobalt complex is prepared through a reaction of a cobalt salt and an NNP ligand or a PNP ligand under the protection of an inert atmosphere;and the chemical formula of the cobalt salt is CoX12, wherein X1 represents halogen, a sulfate radical, a perchlorate radical, a hexafluorophosphate radical, a hexafluoroantimonate radical, a tetrafluoroborate radical, a trifluoromethanesulfonate radical or a tetra(pentafluorophenyl)borate radical. The cobalt complex can be used in the selective catalysis of the transfer hydrogenation reaction ofthe cyano group to obtain a primary amine compound, a secondary amine compound and a tertiary amine compound, the primary amine compound, the secondary amine compound and the tertiary amine compoundare important intermediates in a series of subsequent functionalizing reactions, and the cobalt complex has a very high catalysis activity, and has great research values and a great application prospect.