651735-59-0

Basic information

• Product Name: 7-Fluoro-1-indanone
• Synonyms: 1H-Inden-1-one,7-fluoro-2,3-dihydro-(9CI);7-fluoro-2,3-dihydroinden-1-one;7-fluoro-2,3-dihydro-1H-inden-1-one;2,3-Dihydro-7-fluoro-1H-inden-1-one, 2,3-Dihydro-7-fluoro-1-oxo-1H-indene;1H-Inden-1-one,7-fluoro-2,3-dihydro-
• CAS NO: 651735-59-0
• Molecular Formula: C₉H₇FO
• Molecular Weight: 150.15
• Product Categories: HALIDE;CYCLOPENTANE
• Mol File: 651735-59-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 245.139 °C at 760 mmHg
• Flash Point: 86.764 °C
• Appearance: /
• Density: 1.259 g/cm³
• Vapor Pressure: 0.0292mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 7-Fluoro-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Fluoro-1-indanone(651735-59-0)
• EPA Substance Registry System: 7-Fluoro-1-indanone(651735-59-0)

Safety Data

• Hazardous Substances Data: 651735-59-0(Hazardous Substances Data)

Usage

General Description

7-Fluoro-1-indanone is a chemical compound with the chemical formula C9H7FO. It is an organic compound with a fluoro-substituted indanone structure, which consists of a seven-membered ring with a ketone functional group and a fluorine atom attached to the carbon at position 7. 7-Fluoro-1-indanone is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is known to exhibit a variety of chemical reactions, including nucleophilic addition, substitution, and oxidation reactions, making it a versatile building block in organic synthesis. Additionally, it has potential utility in medicinal chemistry and drug discovery as a key structural motif in the design of bioactive compounds.

InChI:InChI=1/C9H7FO/c10-7-3-1-2-6-4-5-8(11)9(6)7/h1-3H,4-5H2

Upstream product

• 898767-04-9 3-chloro-1-(2-fluorophenyl)propan-1-one 
• 50-00-0 formaldehyd 
• 108-59-8 malonic acid dimethyl ester 
• 445-29-4 o-fluoro-benzoic acid 
• 71095-56-2 1-(2-bromophenyl)-2-propen-1-one 
• 2142-69-0 2-bromophenyl methyl ketone 
• 74-85-1 ethene 
• 393-52-2 2-Fluorobenzoyl chloride 
• 628732-03-6 7-amino-2,3-dihydro-1H-inden-1-one 
• 77802-37-0 N-(2,3-dihydro-1H-inden-4-yl)acetamide 
• 32202-61-2 4-aminoindan 
• 58161-36-7 N-(3-oxo-2,3-dihydro-1H-inden-4-yl)acetamide 

Downstream Products

• 2676863-29-7 5-cyclopropyl-7-fluoro-2,3-dihydro-1H-inden-4-amine 
• 2676863-53-7 7-fluoro-5-isopropyl-2,3-dihydro-1H-inden-4-amine 
• 2260959-53-1 5-bromo-7-fluoro-2,3-dihydro-1H-inden-4-amine 
• 2260959-52-0 7-fluoro-2,3-dihydro-1H-inden-4-amine 
• 2260959-50-8 7-fluoro-4-nitro-2,3-dihydro-1H-inden-1-ol 
• 1092347-71-1 7-fluoro-4-nitro-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

Rh-Catalyzed Annulation of Benzoic Acids, Formaldehyde, and Malonates via ortho-Hydroarylation to Indanones

A three-component reaction from readily available low-cost materials of benzoic acids, formaldehyde, and malonates for the preparation of indanones by rhodium catalysis is reported. The annulation is initiated by an ortho-hydroarylation of benzoic acids, and a Lewis acid is not required. The solvent has a significant influence to the reaction, and 2-substituted or nonsubstituted indanones are obtained by the change of solvent.

CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES

The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a carbamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a carbamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.

NOVEL COMPOUND, AND KINESIN SPINDLE PROTEIN INHIBITOR AND APPLICATION THEREOF

A compound represented by the following General Formula (I): where, in General Formula (I), R1 and R2 each represent an alkyl group which may have a substituent, R3 represents the following General Formula (II) or (III), and R1 and R2 may be identical or different, where, in General Formulas (II) and (III), X represents a hydrogen atom or a halogen atom, R4 represents a methyl group, a dimethyl group or an oxygen atom, and * represents a binding position.