6528-75-2

Usage

Type

Benzimidazole derivative

Use

UV filter in sunscreens and cosmetic products

Function

Absorbs and blocks UV radiation

Protection

Against skin damage and premature aging caused by sun exposure

Sunlight Absorption

Effectively absorbs both UVA and UVB rays

Safety

Considered safe for use in cosmetics

Skin Irritation Potential

Low

Photostability

High

Upstream product

• 75-03-6 ethyl iodide 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 10112-15-9 N-Ethyl-2-nitroaniline 
• 23838-73-5 N-ethyl-benzene-1,2-diamine 
• 100-52-7 benzaldehyde 
• 7035-68-9 1-Ethylbenzimidazole 
• 100-66-3 methoxybenzene 
• 95-54-5 1,2-diamino-benzene 
• 4903-36-0 N-phenyl-benzimidoyl chloride 
• 93-98-1 N-phenyl benzoyl amide 
• 1609460-61-8 N-ethyl-N′-phenylbenzimidamide 
• 1006-93-5 N-ethylchloro(phenyl)methanimine 
• 614-17-5 N-ethylbenzamide 
• 74-96-4 ethyl bromide 

Relevant academic research and scientific papers

Synthesis and antiproliferative activity of benzimidazole-based, trinuclear neutral cyclometallated and cationic, N^N-chelated ruthenium(ii) complexes

A series of 2-phenyl and 2-pyridyl tris-benzimidazole ligands was reacted with the [Ru(p-cymene)Cl2]2 dimer to yield the corresponding neutral cyclometallated and cationic organoruthenium(ii) complexes. All of the synthesized compoun

Neutral heteroleptic cyclometallated Platinum(II) complexes featuring 2-phenylbenzimidazole ligand as bright emitters in solid state and in solution

A series of 8 neutral cyclometallated platinum(II) complexes featuring 2-phenylbenzimidazole chromophoric ligand and acetylacetonate as ancillary ligand has been synthesized and characterized. The introduction of a variety of substituent on the phenyl ring allows to finely tune the emission wavelength. The emission data reveal high quantum yield in deaerated solution and in bulk solid state (micro-crystalline powder), with values up to an impressive 51%. The emission for all of the complexes is attributed to a mixed 3LC-MLCT state. Both absorption and emission data have been correlated successfully with the redox potentials and the Hammett parameters.

Nickel-Catalyzed Heteroarenes Cross Coupling via Tandem C-H/C-O Activation

Inert aryl methyl ethers as coupling components via C-O activation have been established with a Ni catalyst for C-H activation of heteroarene. The key to simultaneous C-H/C-O bond activation is the use of sterically demanding o-tolylMgBr. The protocol is effective for a wide scope of substrates including naphthyl methyl ethers, anisoles, and a variety of other heteroarene derivatives. Detailed mechanistic studies indicated that the C-O cleavage is assisted via synergistic effect of nickel and Grignard reagent in this C-H/C-O reaction, which is supported by DFT calculation. At this stage, single-electron transfer can be ruled out as a main operative process for this tandem strategy.

Synthesis of benzimidazoles via iridium-catalyzed acceptorless dehydrogenative coupling

Iridium-catalyzed acceptorless dehydrogenative coupling of tertiary amines and arylamines has been developed. A number of benzimidazoles were prepared in good yields. An iridium-mediated C-H activation mechanism is suggested. This finding represents a novel strategy for the synthesis of benzimidazoles.

Synthesis of benzimidazoles via iridium-catalyzed acceptorless dehydrogenative coupling

Iridium-catalyzed acceptorless dehydrogenative coupling of tertiary amines and arylamines has been developed. A number of benzimidazoles were prepared in good yields. An iridium-mediated C-H activation mechanism is suggested. This finding represents a novel strategy for the synthesis of benzimidazoles.

Simultaneous modification of N-alkyl chains on cyclometalated and ancillary ligands of cationic iridium(III) complexes towards efficient piezochromic luminescence properties

In this study, we have designed and synthesized a series of multifunctional cationic iridium(iii) complexes with different lengths of N-alkyl chains on 2-phenyl-1H-benzimidazole-based cyclometalated ligands and phenyl-pyridine type ancillary ligands. The

Synthesis and optical properties of novel fluorescence-traced benzimidazolium bromides

Seven novel fluorescence-traced 1-aryl-2-substituted-3-allyl-1H- benzimidazolium bromides (5a, 5b, 5c, 5d, 5e, 5f, 5g) were synthesized by alkylation and quaternization of compounds 1-aryl-2-substituted-1H- benzimidazoles (4a, 4b, 4c, 4d, 4e, 4f, 4g) with excess allyl bromide in acetonitrile at refluxing temperature. Their structures were characterized by 1H-NMR, MS, and elemental analysis. They emit violet-blue light (λEmmax = 386-438 nm) with fluorescence quantum yields of 0.54 to 0.75 in aqueous solution.

Solvent/oxidant-switchable synthesis of multisubstituted quinazolines and benzimidazoles via metal-free selective oxidative annulation of arylamidines

A fast and simple divergent synthesis of multisubstituted quinazolines and benzimidazoles was developed from readily available amidines, via iodine(III)-promoted oxidative C(sp3)-C(sp2) and C(sp 2)-N bond formation in nonpolar and polar solvents, respectively. Further selective synthesis of quinazolines in polar solvent was realized by TEMPO-catalyzed sp3C-H/sp2C-H direct coupling of the amidine with K2S2O8 as the oxidant. No metal, base, or other additives were needed.

Effect of alkyl chain length on piezochromic luminescence of iridium(III)-based phosphors adopting 2-phenyl-1H-benzoimidazole type ligands

In this work, a series of luminescent cationic iridium(iii) complexes containing 2-phenyl-1H-benzimidazole-type ligands modified with n-alkyl chains of various lengths have been successfully synthesized and characterized. Their photophysical and electroch

Synthesis, characterization, optical properties and theoretical calculations of blue light-emitting 1-alkyl-2-substituted benzimidazoles

A series of novel blue light-emitting 1-alkyl-2-substituted benzimidazoles (4a-4g) were synthesized by reactions of the 2-substituted benzimidazoles (3a-3e) with ethyl bromide or n-butyl bromide as electrophilic reagent. Compounds 3a, 3c, 3e were synthesized by the condensation of 1a-1c with 1,2-diamino benzene o-phenylene diamine using air as oxidizing agent and compounds 3b, 3d were synthesized by the condensation of 2d-2e with 1,2-diamino benzene o-phenylene diamine using phosphoric acid and polyphosphoric acid as catalyst. Their optical properties were investigated by UV-visible spectroscopy and photoluminescence techniques in solution. They emit violetblue light (lEm max = 380-440 nm) with fluorescence quantum yields of 0.43 to 0.92 while diluted in acetonitrile solution. In order to find the relationship between the structures and properties of compounds 4a-4g, theoretical calculations using density functional theory at the B3LYP/6-31g*level were also studied.