65398-69-8

Upstream product

• 18800-53-8 3,4-dimethylthiophenol 
• 77-78-1 dimethyl sulfate 
• 371-15-3 p-fluorothioanisole 
• 74-88-4 methyl iodide 
• 1073-14-9 4,4-dimethylcyclohexa-2,5-dienone 
• 3908-55-2 Trimethyl(methylthio)silane 

Downstream Products

• 65398-68-7 Thiocarbonic acid S-(4,5-dimethyl-2-methylsulfanyl-phenyl) ester O-methyl ester 
• 74-87-3 methylene chloride 
• 18800-53-8 3,4-dimethylthiophenol 
• 123159-38-6 2,3,6,7-Tetramethyl-9,10-dithia-4b,9a-diphospha-indeno[1,2-a]indene 
• 37734-36-4 4,5-dimethyl-benzene-1,2-dithiol 
• 22884-95-3 3,4-dimethylbenzonitrile 
• 38417-53-7 1,2-dimethyl-4-(methylsulfinyl)benzene 

Relevant academic research and scientific papers

Novel dienone-phenol type rearrangement of 4,4-disubstituted cyclohexadienone system using thiosilane

Thiosilane and a catalytic amount of a Bronsted acid mediate the novel domino-type rearrangement reaction of the 4,4-disubstituted cyclohexadienones to produce the 3,4-disubstituted benzenethioethers; the key step is 1,2-addition of thiosilane to dienone.

Metallation reactions. XXV. A re-examination of the metallation reaction of (alkylthio)fluorobenzenes

The metallation of (alkylthio)fluorobenzenes by organolithium compounds, lithium amides and butyllithium/potassium tert-butoxide superbasic mixture was re-examined. To avoid the formation of defluorinated compounds all the reactions must be carried out below -80°C. The para-substituted 1a and 1b showed a regiochemistry directed by the halogen; the ortho-derivative 1c underwent metallation ortho to the halogen when treated with lithium tetramethylpiperidide, an α-metallation with butyllithium while sec-butyllithium was less selective. Compounds 1a and 1c allowed the preparation of disubstituted products. At temperatures higher than -80°C increasing amounts of dehalogenated products are formed, whose formation can be explained through the intermediacy of arynes.

The Reaction of Alkyl-substituted Thioanisoles with PCl3 and AlCl3: a Route to Benzothiadiphospholobenzothiadiphosphole Derivatives

The synthesis of benzothiadiphospholobenzothiadiphosphole derivatives starting from alkyl-substituted thioanisoles and PCl3-AlCl3 is reported.The reaction is carried out at reflux in the absence of solvent and the yields are dependent on the starting sulphide.These new heterocycles can be purified by simple filtration on a Florisil column and have been characterized by 1H-, 13C-, (1H)31P-n.m.r. and mass spectroscopy analyses.New unexpected findings are also described.