65875-39-0

Usage

Category

Chemical compound

Function

Antihistamine and anticholinergic medication

Medical Uses

Treats allergic reactions, hay fever, and pruritus (itching)

Mechanism of Action

Blocks the effects of histamine, a substance that causes allergy symptoms

Administration

Typically administered orally or topically

Onset of Action

Relatively rapid

Side Effects

May cause drowsiness and other central nervous system side effects

Precautions

Should be used with caution in individuals operating heavy machinery or vehicles

Dosage

Follow dosing instructions provided by a healthcare professional

Upstream product

• 91907-70-9 N'-(4-methoxy-benzylidene)-N,N-dimethyl-ethylenediamine 
• 2393-23-9 4-methoxy-benzylamine 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 86154-87-2 (2-chloro-ethyl)-(4-methoxy-benzyl)-amine 
• 124-40-3 dimethyl amine 
• 3717-21-3 p-methoxyl benzaldoxime 

Downstream Products

• 91-85-0 thonzylamine 
• 91-84-9 pyrilamine 
• 96588-34-0 N',N'-Dimethyl-N-<4-methoxy-benzyl>-N-fluorenyl-(9)-aethylendiamin 

Relevant academic research and scientific papers

Photoredox-catalyzed decarboxylative cross-coupling of α-amino acids with nitrones

A decarboxylative cross-coupling reaction of α-amino acids with nitrones via visible-light-induced photoredox catalysis has been established for easy access to β-amino hydroxylamines and vicinal diamines with structural diversity, which is featured with simple operation, mild conditions, readily available α-amino acids, and a broad scope of nitrone substrates. The application of this protocol can furnish efficient synthetic strategies for some valuable vicinal diamine-containing molecules.

Antihistaminic 2-(amino ethylamino) pyridines

The present invention provides a compound of the formula (I): STR1 or a salt, ester or amide thereof; wherein R1 is --COOH, --CH=CH--COOH, --CH2 COOH, or (CH2)2 COOH. R2 is alkoxy (1-4 carbons), alkyl (1-4 carbons), hydrogen, or halogen. R3 and R4 may be the same or different and can be hydrogen, or lower alkyl(1-4 carbons) or NR3 R4 is pyrrolidino. Also disclosed are methods for the preparation of the above compounds and pharmaceutical formulations containing them. The above compounds have antihistaminic activity.