65921-30-4

Usage

Uses

Used in Scientific Research:
2-(4-nitrophenyl)-2-oxoethyl acetate is used as a research chemical for various scientific studies and experiments. It serves as a valuable compound in the exploration of chemical reactions and properties.
Used in Organic Syntheses:
In the field of organic chemistry, 2-(4-nitrophenyl)-2-oxoethyl acetate is used as an intermediate or reagent in the synthesis of more complex organic molecules. Its unique structure allows it to be a key component in the creation of new compounds with potential applications in various industries.

InChI:InChI=1/C10H9NO5/c1-7(12)16-6-10(13)8-2-4-9(5-3-8)11(14)15/h2-5H,6H2,1H3

Upstream product

• 34006-49-0 2-chloro-1-(4-nitrophenyl)ethanone 
• 127-09-3 sodium acetate 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 108-24-7 acetic anhydride 
• 99-81-0 4-Nitrophenacyl bromide 
• 127-19-5 N,N-dimethyl acetamide 
• 71-50-1 acetate 
• 937-31-5 (4-Nitrophenyl)acetylene 
• 127-08-2 potassium acetate 

Downstream Products

• 14922-36-2 4-nitrophenylglyoxylic acid 
• 77977-74-3 (S)-(+)-1-(4-nitrophenyl)-1,2-ethanediol 
• 77977-74-3 (R)-(-)-1-(4-nitrophenyl)-1,2-ethanediol 
• 1239347-32-0 2-acetoxymethyl-2-(4-nitrophenyl)-2,3-dihydroquinazolin-4(1H)-one 
• 62830-97-1 2-(4-aminophenyl)-2-oxoethyl acetate 
• 99282-59-4 1-(4-aminophenyl)-2-hydroxyethan-1-one 
• 501693-47-6 4-amino-3-(4-aminophenyl)furo[2,3-d]pyrimidine 
• 287944-27-8 (S)-(+)-N-(4-(1,2-dihydroxyethyl)phenyl)methanesulfonamide 
• 287944-34-7 (S)-(+)-1-(4-aminophenyl)-1,2-ethanediol 

Relevant academic research and scientific papers

Imidazolium-Based Ionic Network as a Robust Heterogeneous Catalyst in Synthesis of Phenacyl Derivatives

A new imidazolium-based poly(ionic liquid) has been synthesized and used as a robust heterogeneous catalyst for the preparation of phenacyl derivatives by an SN2 reaction of different phenacyl bromides with a broad range of nucleophiles. The products are obtained in high yields under mild conditions. The catalyst can be recycled efficiently.

PhI(OAc)2-promoted umpolung acetoxylation of enamides for the synthesis of α-acetoxy ketones

Umpolung is a fundamental concept in organic chemistry, which provides an alternative strategy for the synthesis of target compounds which were not easily accessible by conventional methods. Herein, a mild and efficient PhI(OAc)2-promoted umpolung acetoxylation reactions of enamides was developed for the synthesis of α-acetoxy ketones. The reaction tolerates a wide range of functional groups and affords α-acetoxy ketones in good to excellent yields. PhI(OAc)2 serves as a source of acetoxy in the reaction.

Novel and efficient transformation of enamides into α-acyloxy ketones via an acyl intramolecular migration process

Hydrogen peroxide and anhydride mediated transformation of enamides to afford substituted α-acyloxy ketones is described. This transition-metal-free cascade reaction has a broad substrate scope and high efficiency. The acyl intramolecular migration procedure successfully achieved this acyloxylation process under mild conditions and increased the atom efficiency.

A process for preparing 4-amino-3 - (4-aminophenyl) furo [2,3-d] pyrimidine method

The invention discloses a method for preparing 4-amino-3-(4-aminobenzene)furo[2,3-d] pyrimidine. The method comprises the following steps: using nitroacetophenone as a raw material, reacting the nitroacetophenone and N-bromo-succinimide to generate 2-brom

Integration of aqueous biphasic with magnetically recyclable systems: Polyethylene glycol-grafted Fe3O4 nanoparticles catalyzed phenacyl synthesis in water

The present work trends to define an efficient phenacyl catalytic synthesis method employing a new nano-magnetite-supported organocatalyst. Polyethylene glycol (PEG) was bonded successfully onto silica coated ferrite and the resultant nanoparticles (PEG@SiO2@Fe3O4) characterized by fourier transform infrared spectroscopy (FT-IR), atomic force microscopy (AFM), thermal gravimetric analysis (TGA), vibrating sample magnetometry (VSM), energy dispersive X-ray analysis (EDAX) and X-ray diffraction (XRD) that exhibited a good catalytic activity in the reaction. The nanoparticles could be easily separated from the reaction mixture by an external magnet and reused in seven reaction cycles without significant loss of activity.

Synthesis, characterization and application of β-cyclodextrin-silica nanocomposite as potential microvessel in nucleophilic substitution reaction of phenacyl halides

In the present study, β-cyclodextrin-silica hybrid is synthesized as a novel, efficient and eco-friendly microvessel and solid-liquid phase-transfer catalyst. This molecular host system was applied for nucleophilic substitution reaction of phenacyl halide

Silver(I)-catalyzed reaction of terminal alkynes with (diacetoxyiodo) benzene: A convenient, efficient and clean preparation of α-acetoxy ketones

Silver(I)-catalyzed reaction of terminal alkynes with (diacetoxyiodo) benzene in wet acetonitrile at room temperature afforded the corresponding α-acetoxy ketones in 55-93% yields. The salient features of this reaction are the effective utilization of PhI

β-cyclodextrin immobilized onto dowex resin: A unique microvessel and heterogeneous catalyst in nucleophilic substitution reactions

The catalytic activity of β-cyclodextrin immobilized on Dowex resin as an efficient solid-liquid phase transfer catalyst was developed for the synthesis of alkyl thiocyanates and phenacyl derivatives in water. The nucleophilic substitution reactions were performed under mild reaction condition and gave the products in excellent yields. Furthermore, the catalyst could be recycled by facile separation without any loss of activity.

A sustainable byproduct catalyzed domino strategy: Facile synthesis of α-formyloxy and acetoxy ketones via iodination/nucleophilic substitution/hydrolyzation/oxidation sequences

The sustainable byproduct catalyzed domino strategy has been performed for the facile synthesis of α-formyloxy and acetoxy ketones via iodination/nucleophilic substitution/hydrolyzation/oxidation sequences from simple and readily available aromatic ketone

Study of anthranilate cyclisation to 2-hydroxymethyl-2,3-dihydroquinazolin- 4(1H)-ones and an alternative synthetic route

Applicability of the previously described rearrangement of 2-oxo-2-phenylethyl 2-amino-benzoate leading to 2-phenyl-2-hydroxymethyl-2,3- dihydroquinazolin-4(1H)-one has been studied. To test the limits of the reaction, various starting compounds such as 2