6626-23-9

Usage

Uses

Used in Chemical Synthesis:
1-CHLOROMETHYL-2-METHYLNAPHTHALENE is used as an intermediate in the production of dyes, pesticides, and pharmaceuticals due to its ability to undergo various chemical reactions and form new compounds.
Used in Organic Chemistry Reactions:
As a reagent, 1-CHLOROMETHYL-2-METHYLNAPHTHALENE is utilized in organic chemistry for its potential to participate in a range of reactions, contributing to the synthesis of complex organic molecules.
Used in Dye Production:
1-CHLOROMETHYL-2-METHYLNAPHTHALENE is used as a chemical intermediate for the synthesis of dyes, where its specific properties allow for the creation of a variety of colorants used in different industries.
Used in Pesticide Formulation:
In the agricultural industry, 1-CHLOROMETHYL-2-METHYLNAPHTHALENE serves as a precursor in the development of pesticides, contributing to the production of effective and targeted crop protection agents.
Used in Pharmaceutical Manufacturing:
1-CHLOROMETHYL-2-METHYLNAPHTHALENE is employed as a building block in the synthesis of pharmaceutical compounds, playing a crucial role in the development of new drugs and medications.
Safety Precautions:
Due to its potentially hazardous nature, 1-CHLOROMETHYL-2-METHYLNAPHTHALENE requires proper handling and safety measures to prevent adverse effects on health and the environment.

InChI:InChI=1/C24H23FN2O4S/c1-5-31-24(30)19-15(4)20(22(29)26-18-10-9-13(2)11-14(18)3)32-23(19)27-21(28)16-7-6-8-17(25)12-16/h6-12H,5H2,1-4H3,(H,26,29)(H,27,28)

Upstream product

• 1706-15-6 α-methyl-1-naphthalenometanol 
• 91-57-6 2-Methylnaphthalene 
• 7647-01-0 hydrogenchloride 
• 50-00-0 formaldehyd 
• 64-19-7 acetic acid 
• 86119-84-8 phosphoric acid 
• 35699-44-6 2-methyl-1-naphthaldehyde 

Downstream Products

• 69815-53-8 (2-methyl-1-napthyl)acetonitrile 
• 573-98-8 dimethyl-1,2 naphtalene 
• 7052-58-6 1,2-bis-(2-methyl-[1]naphthyl)-ethane 
• 1706-15-6 α-methyl-1-naphthalenometanol 
• 32277-35-3 1,2-dihydrocyclobuteno[α]naphthalene 
• 97585-88-1 (2-Methyl-naphthalen-1-ylmethyl)-triphenyl-phosphonium; chloride 
• 78804-14-5 N-cyclohexyl-N-<(2-methyl-1-naphthyl)methyl>benzenesulfinamide 
• 110932-32-6 N-methyl-N-(4'-isopropylbenzyl)-1-(2-methylnaphthalene)methylamine 
• 1064688-26-1 C₃₉H₃₈P₂ 
• 1064688-26-1 C₃₉H₃₈P₂ 
• 1064688-13-6 C₃₈H₃₆P₂ 
• 1064688-13-6 C₃₈H₃₆P₂ 
• 1421365-45-8 C₂₃H₁₉ClN₂O₃ 

Relevant academic research and scientific papers

Pd-catalyzed allylative dearomatisation using Grignard reagents

Pd-catalyzed allylative dearomatisation of naphthyl halides is shown to be feasible by employing Grignard reagents. The high reactivity of the nucleophile allows for fast reactions and low catalyst loading, while a plethora of successfully substituted compounds illustrate the broad scope. Five membered heteroaromatic compounds are also demonstrated to be reactive under similar conditions.

Pd-catalyzed C4-Dearomative Allylation of Benzyl Ammoniums with Allyltributylstannane

A dearomative C4-allylation of benzyl ammoniums with allyltributylstannane by a palladium catalysis is described. A triarylphosphine-ligated palladium catalyst, which is capable of cleaving benzylic CN bonds, realized facile dearomative reactions with C4 selectivity. Combined with precedented C2- A nd C3-selective functionalizations of benzyl amine derivatives, the present reaction can provide a new synthetic option for the synthesis of multi-substituted alicyclic compounds as well as aromatic compounds.

1,2-butene and second hydrogen cyclo [α] naphtalenes new synthetic method

The invention discloses a novel synthetic method of 1,2-dihydro cyclobutene [alpha] naphthalene, which comprises the following steps that (1) 2-methylnaphthalene, paraformaldehyde, glacial acetic acid and hydrochloric acid are directly fed; heating and reaction are performed at 60-70 DEG C; a 1-chloromethane-2-methylnaphthalene crude product is prepared; (2) the obtained 1-chloromethane-2-methylnaphthalene crude product is subjected to reduced pressure distillation; unconverted 2-methylnaphthalene is removed; high-purity 1-chloromethane-2-methylnaphthalene is obtained; (3) high-purity 1-chloromethane-2-methylnaphthalene is added to a pyrolyzer for pyrolysis; a 1,2-dihydro cyclobutene [alpha] naphthalene crude product is obtained; and (4) the 1,2-dihydro cyclobutene [alpha] naphthalene crude product is dried, distilled, subjected to column chromatography and condensed; and a target product is obtained. Compared with the prior art, the method takes 2-methylnaphthalene as a basic raw material to prepare 1,2-dihydro cyclobutene [alpha] naphthalene by chloromethylation and pyrolysis cyclization, and is mild in synthetic condition, high in yield, very high in production value and good in industrial prospect.