6626-57-9

Usage

Uses

Used in Organic Synthesis:
1,3-Dichloro-2,2-dimethoxypropane is used as a reagent for the protection of alcohols in organic synthesis for the formation of acetals. It serves as a crucial intermediate in the synthesis of various organic compounds, providing a stable and easily removable protecting group for alcohols during chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3-Dichloro-2,2-dimethoxypropane is used as a key intermediate in the synthesis of certain pharmaceutical compounds. Its ability to protect alcohols as acetals allows for the selective modification of complex organic molecules, facilitating the development of new drugs and therapeutic agents.
Used in Chemical Research:
1,3-Dichloro-2,2-dimethoxypropane is also utilized in chemical research as a versatile reagent for the study of organic reactions and mechanisms. Its unique properties and reactivity make it a valuable tool for exploring new synthetic pathways and understanding the behavior of various organic compounds.
Used in Material Science:
In the field of material science, 1,3-Dichloro-2,2-dimethoxypropane can be employed as a component in the synthesis of novel materials with specific properties. Its ability to form acetals with alcohols can be leveraged to create new polymers, coatings, or other materials with tailored characteristics for various applications.

InChI:InChI=1/C5H10Cl2O2/c1-8-5(3-6,4-7)9-2/h3-4H2,1-2H3

Upstream product

• 534-07-6 1,3-Dichloroacetone 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 
• 67-64-1 acetone 

Downstream Products

• 534-07-6 1,3-Dichloroacetone 
• 341978-82-3 1-benzyl-3,3-dimethoxyazetidine 

Relevant academic research and scientific papers

Preparing method for 1,1,3-trichloroacetone

The invention relates to a preparing method for 1,1,3-trichloroacetone. The preparing method comprises the following process steps that firstly, acetone and methyl alcohol serve as raw materials, an intermediate product 1,3-dichloroacetone dimethyl carbinol is obtained through chlorine chlorination preparation, a crude 1,1,3-trichloroacetone product is obtained through methyl alcohol stripping and deep chlorination, and a pure product is obtained through rectification. According to an improvement of the preparing mehtod, 1,3-dichloroacetone dimethyl carbinol easy to separate is prepared firstly from acetone, by-products 1,1-dichloroacetone and 1,1,1-trichloroacetone are separated out, then carbonyl is reduced through the method of introducing chlorine, new substances cannot be introduced, the purity of the end product1,1,3-trichloroacetone is high, and the total yield through the three-step reaction is high.

GENERAL SYNTHESIS OF CYCLOPROPENONES AND THEIR ACETALS

Metalated cyclopropenone acetals 5 react with a variety of electrophiles, including alkyl halides, carbonyl compounds, vinyl iodides, vinyl triflates, and aryl iodides, to give substituted cyclopropenone acetals in high yield.Hydrolysis of the acetal unde

Chlorination of Aliphatic Ketones in Methanol

The chlorination of aliphatic ketones in methanol has been examined.The product distributions in methanol differ substantially from those obtained by chlorination in carbon tetrachloride.The reaction in methanol favors addition of chlorine to the least substituted carbon α to the carbonyl group.The effect is especially pronounced if an α carbon bearing two substituents is present.The distribution of products is determined by the relative stability of the enol ethers formed from the ketone under the reaction conditions.

Process for the preparation of selectively and symmetrically di-halogenated ketals

A method is disclosed wherein selectively halogenated ketals are prepared by treating ketones and ketals with halogen in an organic solvent under conditions of ordinary temperature and pressure. This process obviates the need for extreme times, temperatures, and complex equipment while resulting in higher yields than obtained heretofore.

Process for the preparation of selectively halogenated ketals

A method is disclosed wherein selectively halogenated ketals, and ultimately, halogenated ketones are prepared by treating secondary alcohols or halohydrins with halogen in an organic solvent under conditions of ordinary temperature and pressure. This method obviates the need for extreme times, temperatures and complex equipment while resulting in higher yields than obtained heretofore.

Process for the preparation of selectively halogenated ketals

A method is disclosed wherein selectively halogenated ketals and ultimately, halogenated ketones are prepared by treating secondary ethers with halogen in an organic solvent under conditions of ordinary temperature and pressure. This method obviates the need for extreme times, temperatures, and complex equipment.