66469-86-1

Basic information

• Product Name: ETHYL 2,5-DIMETHOXYPHENYLACETATE
• Synonyms: ETHYL 2,5-DIMETHOXYPHENYLACETATE;HOMOGENTISIC ACID ETHYL ESTER;Ethyl 2-(2,5-dimethoxyphenyl)acetate
• CAS NO: 66469-86-1
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;C12 to C63;Carbonyl Compounds;Esters
• Mol File: 66469-86-1.mol

Chemical Properties

• Boiling Point: 162-165 °C8 mm Hg(lit.)
• Flash Point: 160 °F
• Appearance: /
• Density: 1.12 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000633mmHg at 25°C
• Refractive Index: n20/D 1.513(lit.)
• CAS DataBase Reference: ETHYL 2,5-DIMETHOXYPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2,5-DIMETHOXYPHENYLACETATE(66469-86-1)
• EPA Substance Registry System: ETHYL 2,5-DIMETHOXYPHENYLACETATE(66469-86-1)

Safety Data

• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 66469-86-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O4/c1-4-16-12(13)8-9-7-10(14-2)5-6-11(9)15-3/h5-7H,4,8H2,1-3H3

Upstream product

• 1758-25-4 (2,5-dimethoxyphenyl)acetic acid 
• 1201-38-3 2',5'-dimethoxyacetophenone 
• 116632-49-6 (2,5-dimethoxy-phenyl)-pyruvic acid 
• 6202-39-7 homogentisic acid methyl ester dimethyl ether 
• 129667-23-8 ethyl 2-chloro-2-(butylthio)acetate 
• 150-78-7 1,4-dimethoxybezene 
• 64-17-5 ethanol 
• 52711-92-9 2,5-dimethoxyphenylacetyl chloride 
• 18086-24-3 2-(2,5-dimethoxyphenyl)acetonitrile 

Downstream Products

• 3718-97-6 N-(6-chlorobenzothiazole-2-yl)-2-(2,5-dimethoxyphenyl)acetamide 
• 710324-46-2 3-(2,4-Dichloro-pyrimidin-5-yl)-2-(2,5-dimethoxy-phenyl)-propionic acid ethyl ester 
• 66397-42-0 Ethyl-2.6-dimethyl-8-(2'.5'-dimethoxyphenyl)octa-2E_.6E-dienoat 
• 50628-18-7 2,6-dimethyl-8-(2,5-dimethoxyphenyl)octa-2,6-dienal 
• 66397-43-1 8-(2,5-dimethoxyphenyl)-2,6-dimethylocta-2,6-dienol 
• 66397-40-8 2-Methyl-3-vinyloxy-4-(2',5'-dimethoxyphenyl)-but-1-en 
• 66397-39-5 2-Methyl-3-hydroxy-4-(2',5'-dimethoxyphenyl)-but-1-en 
• 33567-62-3 2-(2,5-dimethoxyphenyl)acetaldehyde 
• 99187-42-5 2-(2,5-dimethoxyphenyl)ethylbromide 
• 76196-47-9 ethyl (1,4-benzoquinolyl)acetate 
• 767264-65-3 (+/-)-3-(2,5-dimethoxyphenyl)piperidine 
• 150129-95-6 (+/-)-3-(2,5-dimethoxyphenyl)piperidin-2-one 
• 7417-19-8 2-(2,5-dimethoxyphenyl)ethanol 

Relevant articles and documents

1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof

The invention relates to combinatorial libraries containing two or more novel piperidine-3-carboxamide derivative compounds, methods of preparing the piperidine-3-carboxamide derivative compounds and piperidine-3-carboxamide derivative compounds bound to a resin

2,5-Dimethoxy congeners of (+)- and (-)-3-(3-hydroxyphenyl)-N-n- propylpiperidine

p-Dimethoxyaryl analogs of certain potent catechol-derived dopaminergic agonists show dopaminergic properties for which no structure-activity relationship has yet been defined. (S)-3-(3-Hydroxyphenyl)-N-n- propylpiperidine (1, S-'3-PPP') is a dopaminergic

Organic Synthesis with α-Chloro Sulphides. Preparation of Aromatic γ-Lactones from Phenols and α-Chloro Sulphide Carboxylates

Lewis acid-catalysed alkylation of para-substituted phenols using α-chloro sulphides as electrophiles yields sulphenylated γ-lactones which can be desulphurised with zinc in acetic acid or Raney nickel.This synthesis has been applied to p-cresol, 2-naphthol, and two phenolic dihydrocinnamates.Alkylation of 1,4-dimethoxybenzene yields homogentisic acid dimethyl ether after desulphurisation and hydrolysis.

Syntheses of Covalently-Linked Porphyrin-Quinone Complexes (1)

A synthetic route for the preparation of covalently-linked porphyrin-quinone and metalloporphyrin-quinone complexes as models for the phototrap in bacterial photosynthesis is described. 5-(4-Carboxyphenyl)-10,15,20-tritolylporphyrin, prepared by a mixed aldehyde approach, was attached to a benzoquinone center with a propanediol bridge by means of ester linkages.The starting point for the benzoquinone moiety was 2,5-dihydroxyphenylacetic acid, whose hydroquinone function was first protected by preparing its dimethylether.The spacing between the two centers of the complex could be altered simply by varying the length of the bridging group (a diol) employed.Boron tribromide was used to unmask the quinol derivatives in the final coupled products.The zinc(II) derivative of porphyrin quinone comple was prepared ba addition of a saturated solution of zinc acetate in methanol to a solution of the corresponding porphyrin-hydroquinone complex in dichloromethane at room temperature.The structures of these complexes were confirmed by nmr spectroscopy, uv-visible absorption, and mass spectroscopy.Oxidation of the quinol moiety in the covalently-linked complex to its corresponding quinonoid derivative was accomplished by treating a solution of the complex in dichloromethane with a stoichiometric amount of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, a high potential benzoquinone.