66894-06-2

Basic information

• Product Name: 2-NITROCINNAMALDEHYDE
• Synonyms: AKOS BBS-00003259;3-(2-NITROPHENYL)ACRYLALDEHYDE;2'-NITROCINNAMALDEHYDE;2-NITROCINNAMALDEHYDE;2-NITROPHENYLACROLEIN;2-NITROPHENYLACRYLALDEHYDE;TRANS-2-NITROCINNAMALDEHYDE;TRANS-3-(2-NITROPHENYL)-2-PROPENAL
• CAS NO: 66894-06-2
• Molecular Formula: C9H7NO3
• Molecular Weight: 177.16
• EINECS: 215-988-0
• Mol File: 66894-06-2.mol
• Article Data: 35

Chemical Properties

• Melting Point: 127-129 °C(lit.)
• Boiling Point: 124-126 °C
• Appearance: /
• Density: 1.269±0.06 g/cm3(Predicted)
• Storage Temp.: 0-6°C
• BRN: 1073058
• CAS DataBase Reference: 2-NITROCINNAMALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITROCINNAMALDEHYDE(66894-06-2)
• EPA Substance Registry System: 2-NITROCINNAMALDEHYDE(66894-06-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38-43
• Safety Statements: 26-36-36/37
• WGK Germany: 3
• Hazardous Substances Data: 66894-06-2(Hazardous Substances Data)

Usage

General Description

2-NITROCINNAMALDEHYDE is a chemical compound with the molecular formula C9H7NO3. It is a yellow solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-NITROCINNAMALDEHYDE is also used as a flavoring agent in the food industry. It is known to have potential health hazards and should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. Additionally, it is considered to be harmful if swallowed and could cause long-term damage to aquatic life. Overall, 2-NITROCINNAMALDEHYDE is an important chemical compound with a wide range of applications, but it should be used and handled with caution.

Upstream product

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• 82617-88-7 cis-1-chloro-2-(2-nitrophenyl)cyclopropane 

Downstream Products

• 62322-81-0 o-nitro-β-cinnamenyl-acrolein 
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• 117838-43-4 Dimethyl-[2-(2-nitro-phenyl)-quinolin-6-yl]-amine 
• 75059-00-6 3-(2-nitrophenyl)prop-2-enylamine 
• 5278-56-8 2-(o-nitrophenyl)quinoline 
• 82814-15-1 N-(5,6-Dihydro-4H-cyclopentathiazol-2-yl)-N'-[(E)-3-(2-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazine 
• 82814-08-2 N-(5,6-Dihydro-4H-cyclopentaselenazol-2-yl)-N'-[(E)-3-(2-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazine 

Relevant articles and documents

(±)-Camphor sulfonic acid assisted IBX based oxidation of 1° and 2° alcohols

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A useful method for the conversion of olefins to nitro olefins

Triflyl nitrate is easily generated from tetra-n-butylammonium nitrate in CH2Cl2 solution and serves as an effective nitrating agent for a wide range of unsaturated substrates to form nitro olefins.

Heck Reactions of Acrolein or Enones and Aryl Bromides – Synthesis of 3-Aryl Propenals or Propenones and Consecutive Application in Multicomponent Pyrazole Syntheses

3-(Hetero)aryl propenals or propenones are efficiently prepared by a Heck reaction of (hetero)aryl bromides and acrolein or vinyl ketones using Beller's CataCXium Ptb ligand under Jeffery's and Fu's conditions. The formation of these three-carbon building blocks is embedded into consecutive three- and pseudo-four-component syntheses of 3-(hetero)aryl and 3,5-diarylpyrazoles with a broad substitution pattern in moderate to excellent yield.