671240-61-2

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 671240-60-1 N-(3-benzyl-5-hydroxy-pyrazin-2-yl)-4-methyl-benzenesulfonamide 
• 671240-57-6 3-benzyl-piperazine-2,5-dione 2-oxime 
• 671240-60-1 C₁₈H₁₇N₃O₃S 
• 671240-58-7 5-amino-6-benzyl-3,6-dihydro-1H-pyrazin-2-one 
• 93554-83-7 α-aminophenylpropiononitrile hydrochloride 

Downstream Products

• 671240-63-4 2-N-(p-toluenesulfonyl)amide-3-benzyl-5-(4-methoxyphenyl)-pyrazine 
• 853941-53-4 2-amino-3-benzyl-5-(phenylethynyl)pyrazine 
• 853941-52-3 8-benzyl-2-(4-hydroxyphenylmethyl)-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 853941-55-6 8-benzyl-6-phenylethynyl-2-(4-fluorophenylmethyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 123437-48-9 8-benzyl-6-(4-fluorophenyl)-2-(4-hydroxyphenylmethyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 123695-78-3 2-amino-3-benzyl-5-(4-N,N-dimethylaminophenyl)pyrazine 
• 124469-80-3 8-benzyl-6-(N,N-dimethyl-4-aminophenyl)-2-(4-hydroxyphenylmethyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 70217-86-6 2-amino-3-benzyl-5-phenyl-pyrazine 
• 196959-81-6 2-amino-5-(4-fluorophenyl)-3-phenylmethylpyrazine 
• 853941-58-9 8-benzyl-6-(4-(dimethylamino)phenyl)-2-(4-hydroxybenzylidene)imidazo[1,2-a]pyrazin-3(2H)-one 
• 1268631-67-9 8-benzyl-2-(4-hydroxybenzyl)-3-oxo-3,7-dihydroimidazo[1,2-a]pyrazin-6-yl trifluoromethanesulfonate 
• 1268631-78-2 3-benzyl-5-(6-methoxynaphthalen-2-yl)pyrazin-2-amine 
• 1268631-79-3 3-benzyl-5-(biphenyl-4-yl)pyrazin-2-amine 
• 1268631-80-6 3-benzyl-5-(4-phenoxyphenyl)pyrazin-2-amine 

Relevant academic research and scientific papers

Suzuki-Miyaura coupling for general synthesis of dehydrocoelenterazine applicable for 6-position analogs directing toward bioluminescence studies

Synthesis of coelenterazine analogs is in recent demand to supply more luminescent compounds with reasonable stability as substrate for the photoprotein manipulated in a living cells or particular organelle. There are limited methods for the synthesis of

Novel synthetic route of aryl-aminopyrazine

We report a novel synthetic route of aryl-aminopyrazine through a new cyclization reaction by using a hydroxylamine. Starting from Boc-glycine and aminonitrile, the aminopyrazine ring was prepared in several steps. After trifluoromethane sulfonylation of the aminopyrazinone, the resultant triflate was subjected to Suzuki-Miyaura coupling reaction with aryl boronic acid to afford coelenteramine.