67131-27-5

Upstream product

• 100-42-5 styrene 
• 3425-46-5 potassium selenocyanate 
• 98-86-2 acetophenone 
• 4636-16-2 iodoacetophenone 
• 13103-11-2 selenocyanic acid 
• 7677-24-9 trimethylsilyl cyanide 
• 70-11-1 α-bromoacetophenone 
• 109-77-3 malononitrile 
• 4768-87-0 sodium selenocyanate 
• 532-27-4 1-chloroacetophenone 

Downstream Products

• 75200-89-4 [4-(2-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazol-2-yl]-phenyl-methanone 
• 75200-85-0 (5-Imino-4-phenyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-phenyl-methanone 
• 75200-86-1 (5-Imino-4-p-tolyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-phenyl-methanone 
• 75200-88-3 [4-(4-Chloro-phenyl)-5-imino-4,5-dihydro-[1,3,4]selenadiazol-2-yl]-phenyl-methanone 
• 75200-87-2 (5-Imino-4-m-tolyl-4,5-dihydro-[1,3,4]selenadiazol-2-yl)-phenyl-methanone 
• 86098-13-7 4-(5-Benzoyl-2-imino-[1,3,4]selenadiazol-3-yl)-benzoic acid ethyl ester 
• 112565-02-3 2-imino-2,3-dihydro-3-(3-phenyl-5-pyrazolyl)-5-benzoyl-1,3,4-selenadiazole 
• 100-52-7 benzaldehyde 
• 39167-49-2 1,5-diphenyl-3-selena-1,5-pentanedione 
• 81926-96-7 2,2'-diselenediylbis(1-phenylethanone) 
• 495-71-6 phenacylacetophenone 
• 113372-37-5 2-benzoylimino-2,3-dihydro-3-(1-benzoyl-3-phenyl-5-pyrazolyl)-5-benzoyl-1,3,4-selenadiazole 
• 75200-94-1 N-[5-Benzoyl-3-(2-chloro-phenyl)-3H-[1,3,4]selenadiazol-(2Z)-ylidene]-acetamide 
• 75200-93-0 N-[5-Benzoyl-3-(4-chloro-phenyl)-3H-[1,3,4]selenadiazol-(2Z)-ylidene]-acetamide 

Relevant academic research and scientific papers

α-Selective C(sp3)-H Thio/Selenocyanation of Ketones with Elemental Chalcogen

A facile method is disclosed for the synthesis of α-thio/selenocyanato ketones through regioselective C-H thio/selenocyanation of ketones. The advantages include the use of easily available starting materials, high efficiency, simple operation, and easy scale-up. Control experiments provide evidence that the reaction proceeded via a radical way, while kinetic isotope effect experiments reveal that the cleavage of the C-H bond serves as the rate-limiting step.

Solvent free nucleophilic selenocyanation with [bmim][SeCN]. Direct access to perfluoroalkylselenide compounds

Available online-1-n-butyl-3-methylimidazolium selenocyanate ([bmim][SeCN]) proved to be a very efficient reagent for selenocyanation of alkyl halides. As part of an eco-friendly process, no organic solvents were used during the transformation and reaction times are reduced by using microwave as a heating source. The ionic liquid was carefully recycled in two different ways. Selenocyanate compounds were successfully transformed into trifluoromethylselenides in a one-pot two step procedure.

Selenocyanation of Aryl and Styryl Methyl Ketones in the Presence of Selenium Dioxide and Malononitrile: An Approach for the Synthesis of α-Carbonyl Selenocyanates

A convenient method has been developed for the synthesis of α-carbonyl selenocyanates from aryl methyl ketones/styryl methyl ketones using selenium dioxide as the selenating agent under simple reaction conditions. This reaction has notable advantages over the traditional methods in terms of accessibility and affordability of the starting materials. The method features the interaction of aryl methyl ketones/styryl methyl ketones with selenium dioxide and malononitrile to afford a series of α-carbonyl selenocyanates in moderate to good yields.

Synthesis of Thio-/Selenopyrrolines via SnCl4-Catalyzed (3+2)-Cycloadditions of Donor-Acceptor Cyclopropanes with Thio-/Selenocyanates

A straightforward protocol has been developed to access thio-/selenopyrrolines through a (3+2)-cycloaddition of aryl thio-/selenocyanates with donor-acceptor cyclopropanes (DACs) in the presence of SnCl4 as a Lewis acid catalyst. Further, good chemoselectivity was observed when DACs were treated with 3-cyano phenyl thiocyanate. These results suggest that thiocyanate is more reactive than nitrile moiety in such (3+2)-cycloaddition reactions.

Oxidative umpolung selenocyanation of ketones and arenes: An efficient protocol to the synthesis of selenocyanates

A practical method for the umpolung selenocyanation of aryl ketones, alkyl ketones, β-ketoesters and electron-rich arenes has been developed, affording various selenocyanates in moderate to excellent yields. This transformation proceeds by an oxidative um

Selenium cyanation reagent and preparation method and application thereof

The invention discloses a selenium cyanation reagent. A structural formula thereof is as shown in the description. The selenium cyanation reagent has very good organic eletrophilicity. In the application of preparing a compound containing a selenium cyano

A novel metal-free method for the selenocyanation of aromatic ketones to afford α-carbonyl selenocyanates

A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared α-halo ketones, providing rapid access to α-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.

Synthesis, characterization, and structures of α-substituted selenenyl-acetophenones

A series of α-substituted selenenyl acetophenone derivatives of the types, [PhC(OCH2CH2O)CH2Se]2, [PhC(OCH2CH2O)CH2SeR], (PhCOCH2Se) 2, and [PhCOCH2/s

Synthesis of 4-Aryl-2-imino-2H-selenazolines by a reaction of α α-(selenocyanato)acetophenones with anilines

4-Aryl-2-imino-2H-selenazolines have been prepared by a reaction of α-(selenocyanato)acetophenones with anilines.