67287-54-1 Usage
Uses
Fenoldopam Monohydrobromide is a potent D-1 dopamine agonists.
Biochem/physiol Actions
Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.
Check Digit Verification of cas no
The CAS Registry Mumber 67287-54-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,8 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67287-54:
(7*6)+(6*7)+(5*2)+(4*8)+(3*7)+(2*5)+(1*4)=161
161 % 10 = 1
So 67287-54-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H16ClNO3.BrH/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;/h1-4,7,13,18-21H,5-6,8H2;1H
67287-54-1Relevant academic research and scientific papers
Process for the preparation of Fenoldopam Mesylate
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Page/Page column 7, (2008/06/13)
Methods and intermediates for the preparation of Fenoldopam mesylate and intermediates thereof are provided.
Solid oral preparation containing a pyrrolidine derivative with a catechol group
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, (2008/06/13)
An oral solid preparation comprising an organic acid or its salt and a catechol compound. The catechol compound is, for example, a pyrrolidine derivative having a catechol group of the following general formula (I). It exhibits an improved absorbability in vivo. STR1
