19484-05-0

Basic information

• Product Name: 1-((4-methoxy)phenyl)-1,2-dibromoethane
• Synonyms: 1-((4-methoxy)phenyl)-1,2-dibromoethane
• CAS NO: 19484-05-0
• Molecular Weight: 293.986
• Mol File: 19484-05-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1-((4-methoxy)phenyl)-1,2-dibromoethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((4-methoxy)phenyl)-1,2-dibromoethane(19484-05-0)
• EPA Substance Registry System: 1-((4-methoxy)phenyl)-1,2-dibromoethane(19484-05-0)

Safety Data

• Hazardous Substances Data: 19484-05-0(Hazardous Substances Data)

Upstream product

• 637-69-4 4-Methoxystyrene 
• 41824-88-8 1,2-dibromoethyl methyl ether 
• 64-19-7 acetic acid 
• 100-66-3 methoxybenzene 
• 2983-26-8 1,2-dibromoethyl ethyl ether 
• 41683-60-7 (1,2-dibromo-ethyl)-propyl ether 
• 1515-95-3 p-ethylanisole 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 10035-10-6 hydrogen bromide 
• 29338-71-4 1-bromo-1-(4-methoxyphenyl)ethene 
• 34910-42-4 1-(1-azidovinyl)-4-methoxybenzene 
• 637-69-4 4-Methoxystyrene 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 104113-90-8 9-Chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide 
• 104113-95-3 6-Chloro-1-(4-hydroxy-phenyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide 
• 104113-94-2 6-Fluoro-1-(4-hydroxy-phenyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide 
• 72912-26-6 SKF 87516 hydrobromide 
• 75306-60-4 [2-tert-Butoxy-2-(4-methoxy-phenyl)-ethyl]-[2-(2-chloro-3,4-dimethoxy-phenyl)-ethyl]-amine 
• 104113-99-7 [2-tert-Butoxy-2-(4-methoxy-phenyl)-ethyl]-[2-(3,4-dimethoxy-2-methyl-phenyl)-ethyl]-amine 
• 104114-10-5 6-Fluoro-7,8-dimethoxy-1-(4-methoxy-phenyl)-1,2,4,5-tetrahydro-benzo[d]azepine-3-carbaldehyde 
• 104114-00-3 9-Chloro-7,8-dimethoxy-1-(4-methoxy-phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine 
• 104114-12-7 6-Fluoro-7,8-dimethoxy-1-(4-methoxy-phenyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 

Relevant articles and documents

Dihalogenation of Alkenes Using Combinations of N-Halosuccinimides and Alkali Metal Halides

A simple, efficient and eco-friendly method for the vicinal dihalogenation of alkenes is described. The reaction is performed with a combination of a N-halosuccinimide and an alkali metal halide using environmentally benign solvents such as acetic acid an

Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co–Catalyzed, Enantioselective Proton-Transfer

We report an enantioselective Nazarov cyclization catalyzed by chiral hydrogen-bond-donors in concert with silyl Lewis acids. The developed transformation provides access to tri-substituted cyclopentenones in high levels of enantioselectivity (up to 95% e.e.) from a variety of simple unactivated dienones. Kinetic and mechanistic studies are consistent with a reversible 4π-electrocyclization C?C bond-forming step followed by rate- and enantio-determining proton-transfer as the mode of catalysis. (Figure presented.).

A bimetallic palladium(II) catalyzed synthesis of 1,2-dibromo compounds

A bimetallic palladium(II) catalyst containing a triketone ligand and a bridging dinitrogen ligand oxidizes aromatic and cyclic aliphatic olefins in bromide-containing aqueous-THF to 1,2-dibromo compounds and bromohydrins. With aromatic olefins, the 1,2-dibromo products were obtained in a 70-80% yield and the bromohydrins in a 10-15% yield; this observation is opposition to that obtained in chloride containing medium where the chlorohydrin product predominates. The oxidation of 2,3-dihydrofuran gave trans-2,3- dibromotetrahydrofuran, 3-oxotetrahydrofuran, and 3-bromo-2- hydroxytetrahydrofuran in relative yields of 75%, 15%, and 10%, respectively. On the other hand, the oxidation of cyclopentene and cyclohexene affords only trans-1,2-dibromo products in about 90% yield. The stereochemistry is consistent with an anti-at-tack of bromide followed by decomposition involving attack of bromide from the coordination sphere of the Pd(II). The procedure outlined here is a convenient method for the one step synthesis of 1,2-dibromides.