67287-53-0

Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-2,3,4,5-tetrahydro-7,8-dimethoxy-1-(4-methoxyphenyl)-1H-3-benzazepine is used as a potential drug candidate for various medical purposes due to its pharmacological activity. Its specific applications would depend on the results of further research and testing.

InChI:InChI=1/C19H22ClNO3/c1-22-13-6-4-12(5-7-13)16-11-21-9-8-14-15(16)10-17(23-2)19(24-3)18(14)20/h4-7,10,16,21H,8-9,11H2,1-3H3

Upstream product

• 71636-38-9 N-[2-hydroxy-2-(4'-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine 
• 621-59-0 isovanillin 
• 93983-14-3 2-chloro-3,4-dimethoxybenzyl chloride 
• 6388-72-3 2-(4-methoxyphenyl)oxirane 
• 13305-14-1 methyl 2-hydroxy-2-(4-methoxyphenyl)acetate 
• 77-78-1 dimethyl sulfate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 37687-57-3 2-chloro-3-hydroxy-4-methoxybenzaldehyde 
• 19484-05-0 1-((4-methoxy)phenyl)-1,2-dibromoethane 
• 5417-17-4 2-chloro-3,4-dimethoxybenzaldehyde 
• 637-69-4 4-Methoxystyrene 
• 75306-60-4 [2-tert-Butoxy-2-(4-methoxy-phenyl)-ethyl]-[2-(2-chloro-3,4-dimethoxy-phenyl)-ethyl]-amine 
• 72912-33-5 2-bromo-1-(tert-butoxy)-1-(4-methoxyphenyl)ethane 
• 74427-18-2 N-(2-chloro-3,4-dimethoxyphenylethyl)-4-methoxymandelamide 

Downstream Products

• 100166-68-5 2-[6-Chloro-7,8-dimethoxy-1-(4-methoxy-phenyl)-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl]-ethanol 
• 67227-56-9 fenoldopam 
• 110038-79-4 6-Chloro-2,3,4,5-tetrahydro-7-hydroxy-1-(4-hydroxyphenyl)-8-methoxy-1H-3-benzazepine hydrochloride 
• 110039-05-9 6-Chloro-2,3,4,5-tetrahydro-7-hydroxy-8-methoxy-1-(4-methoxyphenyl)-1H-3-benzazepine hydrochloride 
• 67287-54-1 Fenoldopam hydrobromide 
• 100166-63-0 [6-Chloro-7,8-dimethoxy-1-(4-methoxy-phenyl)-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl]-cyclopropyl-methanone 
• 77386-10-8 3-allyl-6-chloro-7,8-dimethoxy-1-(4-methoxyphenyl)2,3,4,5-tetrahydro-1H-3-benzazepine 
• 100166-60-7 6-Chloro-7,8-dimethoxy-1-(4-methoxy-phenyl)-1,2,4,5-tetrahydro-benzo[d]azepine-3-carbaldehyde 
• 81957-59-7 3-cyclopropylmethyl-6-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide 

Relevant academic research and scientific papers

A hand natural Philippines Duopan splitting method

The invention discloses resolution of a D1 dopamine receptor agonist drug and in particular discloses a resolution method of fenoldopam. The resolution method of the D1 dopamine receptor agonist drug comprises the steps of protecting a phenolic hydroxyl group and an amino group in the structure of fenoldopam, then carrying out chemical resolution with a chiral acidic resolution agent to obtain a pure optical isomer, and finally removing a protecting group and salifying to obtain optically pure methanesulfonic acid fenoldopam.

Solid oral preparation containing a pyrrolidine derivative with a catechol group

An oral solid preparation comprising an organic acid or its salt and a catechol compound. The catechol compound is, for example, a pyrrolidine derivative having a catechol group of the following general formula (I). It exhibits an improved absorbability in vivo. STR1

Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

A group of 6,9-disubstituted-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines have dopaminergic activity. Examples of leading species of the invention are 6,9-dichloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and 6,9-dichloro-7,8-dihydroxy-1-(p-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine in the form of an acid addition salt.