675606-03-8

Basic information

• Product Name: Carbamic acid, [(2R)-2-[3-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-3,6- dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]propyl]-, 1,1-dimethylethyl ester
• CAS NO: 675606-03-8
• Molecular Formula: C27H30F3N3O5
• Molecular Weight: 533.548
• Mol File: 675606-03-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(2R)-2-[3-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-3,6- dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]propyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2R)-2-[3-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-3,6- dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]propyl]-, 1,1-dimethylethyl ester(675606-03-8)
• EPA Substance Registry System: Carbamic acid, [(2R)-2-[3-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-3,6- dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]propyl]-, 1,1-dimethylethyl ester(675606-03-8)

Safety Data

• Hazardous Substances Data: 675606-03-8(Hazardous Substances Data)

Upstream product

• 618914-13-9 1-(2,6-difluorobenzyl)-3-(3-oxobutyryl)urea 
• 352303-66-3 5-bromo-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 
• 352303-65-2 N-1-(2,6-difluorobenzyl)-6-methyluracil 
• 167938-56-9 tert-butyl [(2S)-2-hydroxypropyl]carbamate 
• 17751-24-5 N-(2,6-difluorobenzyl) urea 
• 69385-30-4 2,6-difluorobenzylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 352303-67-4 (2-fluoro-3-methoxyphenyl)boronic acid 
• 352303-74-3 3-[2-N-Boc-amino-1-(R)-methylethyl]-5-bromo-1-(2,6-difluorobenzyl)-6-methyluracil 

Relevant articles and documents

Synthesis and Structure-Activity Relationships of 1-Arylmethyl-5-aryl-6-methyluracils as Potent Gonadotropin-Releasing Hormone Receptor Antagonists

Based on the SAR from bicyclic gonadotropin-releasing hormone (GnRH) antagonists such as 6-aminomethyl-7-aryl-pyrrolo [1,2-a] pyrimid-4-ones (5) and 2-aryl-3-aminomethyl-imidazolo-[1,2-a]pyrimid-5-ones (6a,b), a series of novel uracil compounds (8) were d