675868-79-8Relevant academic research and scientific papers
Design, Pharmacokinetic, and Pharmacodynamic Evaluation of a New Class of Soft Anticholinergics
Huang, Fenglei,Browne, Clinton E.,Wu, Whei-Mei,Juhasz, Attila,Ji, Fubao,Bodor, Nicholas
, p. 1681 - 1689 (2007/10/03)
Purpose. To design and evaluate a new class of soft anticholinergics with subtype selectivity. Methods. A new class of soft anticholinergics was designed based on the "inactive metabolite" approach. Four compounds were synthesized. The potency and soft na
