24102-01-0

Basic information

• Product Name: 2-Cyclohexene-1-carboxylic acid, 2-phenyl-
• CAS NO: 24102-01-0
• Molecular Formula: C13H14O2
• Molecular Weight: 202.253
• Mol File: 24102-01-0.mol

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexene-1-carboxylic acid, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexene-1-carboxylic acid, 2-phenyl-(24102-01-0)
• EPA Substance Registry System: 2-Cyclohexene-1-carboxylic acid, 2-phenyl-(24102-01-0)

Safety Data

• Hazardous Substances Data: 24102-01-0(Hazardous Substances Data)

Upstream product

• 21472-50-4 2-hydroxy-2-phenyl-cyclohexanecarboxylic acid 
• 124-38-9 carbon dioxide 
• 771-98-2 1-Phenylcyclohexene 
• 75-05-8 acetonitrile 
• 13747-72-3 ethyl 1,4-dioxa-spiro[4,5]decane-6-carboxylate 
• 24927-50-2 2-Hydroxymethyl-1-phenyl-cyclohexanol 
• 5331-08-8 2-(hydroxymethyl)cyclohexanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 23153-80-2 1,4-dioxaspiro[4.5]dec-6-yl-methanol 

Downstream Products

• 145450-39-1 2-phenyl-2-cyclohexene-1-carbonyl chloride 
• 675868-81-2 8-azabicyclo[3.2.1]oct-3-yl 2-phenylcyclohex-2-enecarboxylate 
• 675868-79-8 (1R,3R,5S)-3-(2-Phenyl-cyclohex-2-enecarbonyloxy)-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid 1-chloro-ethyl ester 
• 675868-83-4 methyl 2-[8-aza-3-(2-phenylcyclohex-2-enylcarbonyloxy)bicyclo[3.2.1]oct-8-yl]acetate 
• 675868-95-8 ethyl 2-[8-aza-3-(2-phenylcyclohex-2-enylcarbonyloxy)bicyclo[3.2.1]oct-8-yl]acetate 
• 24259-15-2 8-aza-8-methylbicyclo [3.2.1]oct-3-yl 2-phenylcyclohex-2-enecarboxylate 

Relevant articles and documents

EtAlCl2/2,6-Disubstituted Pyridine-Mediated Carboxylation of Alkenes with Carbon Dioxide

α-Arylalkenes and trialkyl-substituted alkenes undergo carboxylation with CO2 in the presence of EtAlCl2 and 2,6-dibromopyridine to afford the corresponding α,β- and/or β,γ-unsaturated carboxylic acids. This reaction is suggested to proceed via the electrophilic substitution of EtAlCl2 with the aid of the base, followed by the carbonation of the resulting ate complex. This reaction can be applied to terminal dialkylalkenes by using a mixture of 2,6-di-tert-butylpyridine and 2,6-dibromopyridine.

Catalytic photocarboxylation of 1,1-diphenylethylene with N,N,N′,N′-tetramethylbenzidine and carbon dioxide

Photocarboxylation of 1,1-diphenylethylene with N,N,N′,N′-tetramethylbenzidine (TMB) in MeCN under bubbling of CO2 proceeded with high catalytic efficiency, giving 3,3-diphenylacrylic acid (DPA) and 3-hydroxy-3,3-diphenylpropionic acid (20). The turnover number (TON=(DPA+20)/TMB) reached 17. Similarly, 1-phenyl-1-cyclohexene yielded cis-2-acetamido-2-phenylcyclohexanecarboxylic acid with TON 5.9. As compared with related N,N-dimethylaniline derivatives, TMB is more resistant to photodecomposition, has the much larger absorbance in the S0→S1 transition, and has the lower quenching efficiency by CO2. Probably these factors are partly responsible for the high TON observed for TMB.

Design, Pharmacokinetic, and Pharmacodynamic Evaluation of a New Class of Soft Anticholinergics

Purpose. To design and evaluate a new class of soft anticholinergics with subtype selectivity. Methods. A new class of soft anticholinergics was designed based on the "inactive metabolite" approach. Four compounds were synthesized. The potency and soft na