67605-65-6

Upstream product

• 75400-63-4 2-(α-hydroxy-α-phenyl)methyl pyrrole 
• 79109-29-8 (4-Nitro-phenyl)-(1H-pyrrol-2-yl)-methanol 
• 917-23-7 5,15,10,20-tetraphenylporphyrin 
• 109-97-7 pyrrole 
• 555-16-8 4-nitrobenzaldehdye 
• 100-52-7 benzaldehyde 
• 107798-98-1 5-phenyldipyrromethane 
• 143859-77-2 2,2'-[(4-nitrophenyl)methylene]bis(1H-pyrrole) 
• 872-85-5 pyridine-4-carbaldehyde 

Downstream Products

• 67605-64-5 5-(p-aminophenyl)-10,15,20-triphenylporphine 
• 133513-05-0 5-(4-iodophenyl)-10,15,20-triphenylporphyrin 
• 1065473-90-6 5-(4-nitrophenyl)-10,15,20-triphenylporphyrinatopalladium(II) 
• 67605-64-5 5-(4-aminophenyl)-10,15,20-triphenylporphyrin 

Relevant academic research and scientific papers

On selective functionalization of meso-tetraphenylporphyrin derivatives by Vicarious Nucleophilic Substitution of Hydrogen

The studies on selective derivatization of meso-tetraphenylporphyrin (TPP) using nitration and Vicarious Nucleophilic Substitution of Hydrogen (VNS) are reported. TPP, its metal complexes and N,N-dimethyl substituted derivatives do not enter the VNS reaction. On the other hand, meso-substituted TPP results in the mono-nitration of one phenyl ring and the intermediate obtained, after simple transformation to its metal complex, reacts with carbanions bearing leaving groups at the carbanionic center, according to VNS scheme. This gives new opportunities for the peripheral functionalization of porphyrins. In this work the copper and zinc complexes were investigated.

Spectral studies of protonated and anionic forms of porphyrins with an asymmetric substitution system

The directed synthesis of asymmetrically substituted porphyrins—tetraphenylporphyrine derivatives containing amino acid residues as a functional group, which can be used as “anchor” groups, for incorporation into the structure of a protein molecule, was c

Synthesis and Acid-Base Properties of Tetraphenylporphine Derivatives with Amino Acid “Anchor” Groups

Abstract: Asymmetrically substituted 5,10,15,20-tetraphenylporphyrin derivatives such as5-(4-aminophenyl)10,15,20-triphenylporphine,5-[4-(tyrosinylamino)phenyl]-10,15,20-triphenylporphine and 5-{4-[(N-tert-butoxycarbonyltyrosinyl)amino]phenyl}-10,15,20-tr

Porphyrin phthalocyanine covalent bifunctional graphene nonlinear nano hybrid material and preparation method thereof

The invention relates to a porphyrin phthalocyanine covalent bifunctional graphene nonlinear nanometer hybrid material and a preparation method thereof. The electron porphyrin and the electron-withdrawing phthalocyanine with the strong electron group are bonded to the surface of the graphene through radical addition reaction, charge is obtained through bridging of graphene, and third-order nonlinear performance of the organic - inorganic hybrid material is enhanced. In the invention, amino-substituted tetraphenylporphyrin and amino-substituted pull electron phthalocyanine are reacted through azo salt, so that a novel bifunctional organic-inorganic covalent functionalized nano hybrid material is successfully prepared. , The prepared material has more enhanced nonlinear optical performance in the nanosecond visible light field compared with the traditional materials, and has very strong reference significance.

Photosensitizer-peptoid conjugates for photoinactivation of Gram-negative bacteria: structure-activity relationship and mechanistic studies

Multitarget engagement is considered an effective strategy to overcome the threat of bacterial infection, and antimicrobials with multiple mechanisms of action have been successful as natural chemical weaponry. Here, we synthesized a library of photosensitizer-peptoid conjugates (PsPCs) as novel antimicrobial photodynamic therapy (aPDT) agents. The peptoids, linkers, and photosensitizers were varied, and their structure-antimicrobial activity relationships againstEscherichia coliwere evaluated; PsPC9was indicated to be the most promising photoresponsive antimicrobial agent among the synthesized PsPCs. Spectroscopic analyses indicated that9generated singlet oxygen upon absorption of visible light (420 nm) while maintaining the weakly helical conformation of the peptoid. Mechanistic studies suggested that damage to the bacterial membrane and cleavage of DNA upon light irradiation were the main causes of bactericidal activity, which was supported by flow cytometry and DNA gel electrophoresis experiments. We demonstrated that the optimal combination of membrane-active peptoids and photosensitizers can generate an efficient aPDT agent that targets multiple sites of bacterial components and kills bacteria by membrane disruption and reactive oxygen species generation.

Tetraphenylporphyrin covalent functionalized titanium disulfide nonlinear nanometer hybrid material and preparation thereof

The invention relates to a tetraphenylporphyrin covalent functionalized titanium disulfide nonlinear nanometer hybrid material and a preparation method thereof, wherein the hybrid material is prepared from tetraphenylporphyrin diazonium salt TPP-N. 2

Poly(L-Glutamic Acid)-Drug Conjugates for Chemo- and Photodynamic Combination Therapy

Despite the polymeric vascular disrupting agent (poly(L-glutamic acid)-graft-methoxy poly(ethylene glycol)/combretastatin A4) nanoparticles can efficiently inhibit cancer growth, their further application is still a challenge owing to the tumor

A kind of porphyrin maleimide derivative covalent functionalized molybdenum disulfide nanosheet nonlinear hybrid material and its preparation and application

The present invention relates to a porphyrin maleimide derivative covalent functionalized molybdenum disulfide nanosheet nonlinear hybrid material and its preparation and application, the porphyrin by maleimide and molybdenum disulfide sulfur atom click r

Correlations between functional porphyrin positions and accumulation in cancer cells

Porphyrin is accumulated in tumours due to its interaction with protein. Cancer therapy with porphyrin as a carrier molecule is attracting attention. Porphyrin displays two functional sites termed β- and meso-positions. A correlation between the functiona

Efficient nonlinear-optical behaviors of chiral-amide-bonded porphyrin noncovalent functionalized MWCNTs by terminated pyrene units

Four chiral porphyrins and their derivatives with chiral-amide-bonded terminal pyrene were synthesized and isolated. Structural characterization as well as electronic structure investigations were carried out to understand the effect of bridging an amide-