67795-42-0

Usage

Uses

Used in Pharmaceutical Synthesis:
3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE is used as a building block for the synthesis of pharmaceuticals due to its unique structure and functional groups. Its amine and carboxamide groups facilitate the creation of diverse organic compounds and pharmaceuticals with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE is used as a ligand in metal catalysts. Its ability to bind with metal ions makes it a valuable component in the development of catalysts for various chemical reactions, which can be applied in the synthesis of pharmaceuticals and other organic compounds.
Used in Catalyst Development:
3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE is utilized in the development of catalysts for chemical reactions. Its potential as a ligand in metal catalysts allows for the enhancement of reaction rates and selectivity, which is crucial in the synthesis of complex organic compounds and pharmaceuticals.
Used in Organic Compounds Synthesis:
3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE is also used in the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable component in the creation of a wide range of organic molecules, which can be used in different industries, including pharmaceuticals, materials science, and chemical research.

InChI:InChI=1/C10H11N3OS/c1-4-3-5(2)13-10-6(4)7(11)8(15-10)9(12)14/h3H,11H2,1-2H3,(H2,12,14)

Upstream product

• 758-08-7 Thioglycolamide 
• 14237-71-9 2-chloro-4,6-dimethylnicotinonitrile 
• 54585-47-6 3-cyano-4,6-dimethyl-2-mercaptopyridine 
• 79-07-2 Chloroacetamide 
• 683-57-8 bromo-acetic acid amide 
• 1092075-70-1 N₂,N₂-di-(5-methyl-2-furylmethyl)-3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide 
• 54585-47-6 4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 

Downstream Products

• 52505-57-4 3-Amino-4,6-dimethyl-thieno<2,3-b>pyridin-2-carbonitril 
• 55023-35-3 7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d]pyrimidine-4(1H)-one 

Relevant academic research and scientific papers

Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors

Cdc7 kinase plays a critical role in the regulation of DNA replication in eukaryotic cells and has been proposed as a target for cancer therapy. We have identified a class of Cdc7/Dbf4 inhibitors with a pyrido-thieno-pyrimidine core structure. Synthesis o

Some transformations of tertiary N-furfurylamides of aromatic and heteroaromatic carboxylic acids under acidic conditions

Acid-catalyzed transformations of tertiary N-furfurylamides of ortho-amino substituted aromatic and heteroaromatic carboxylic acids accompanied by elimination of the furfuryl moiety are investigated. Georg Thieme Verlag Stuttgart.

SUBSTITUTED PYRIDO[3',2':4,5]THIENO[3,2-D]PYRIMIDINE-2,4(1 H,3H)-DIONES AND -4(3H)-ONES, SUBSTITUTED THIENO[2,3-D:4,5-D']DIPYRIMIDINE-2,4(1 H,3H)-DIONES AND -4(3H)-ONES, SUBSTITUTED PYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDINE-2,4(1 H,3H)-DIONES AND -4(3H)-ONES, AND SUBSTITUTED FURO[2,3-D:4,5-D']DIPYRIMIDINE-2,4(1 H,3H)-DIONES AN

The invention relates to novel pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1 H,3H)-diones and -4(3H)-one (X=C-H, Y=S), thieno[2,3-d:4,5-d']dipyrimidine-2,4(1 H,3H)-diones and -4(3H)-one (X=N, Y=S), in addition to pyrido[3',2':4,5]furo[3,2-d]pyrimidine-2,4(1 H,3H)-diones and -4(3H)-one (X=C-H, Y=0) and furo[2,3-d:4,5-d']dipyrimidine-2,4(1 H,3H)-diones and -4(3H)-one (X=N, Y=O) of general formulae 1a and 1b. The invention also relates to a method for the production thereof, pharmaceutical preparations containing said compounds and/or tautomers thereof and physiologically compatible salts which can be produced therefrom and/or solvates thereof, in addition to the pharmaceutical use of said compounds, tautomers thereof, salts or solvates, as inhibitors of TNFa-release.

SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES

Disclosed are compounds of formula (I), wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Synthesis and antifungal activity of pyrido[3',2':4,5]thieno[3,2-d]-1,2,3-triazine derivatives

The antimicrobical activity of some pyrido[3'2':4,5]thieno[3,2d]-1,2,3-triazine derivatives has been studied. Some compounds proved effective against microorganisms in vitro, compounds 3a and 3c in particular exhibited antifungal activity, comparable to M