68235-45-0

Upstream product

• 5416-70-6 3-(2-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 98-86-2 acetophenone 
• 135-02-4 ortho-anisaldehyde 
• 5416-70-6 2-methoxychalcone 

Downstream Products

• 87831-10-5 3-hydroxy-3-(2-methoxy-phenyl)-1-phenyl-propan-1-one 
• 75640-14-1 5-(2-methoxyphenyl)-1,3-diphenyl-1H-pyrazole 
• 1217439-23-0 C₂₄H₂₁NO₃ 
• 1839-72-1 2-phenylbenzofuran 
• 27356-33-8 2-(2-methoxyphenyl)-1-phenylethan-1-one 
• 854630-15-2 2-(2-methoxyphenyl)-3-oxo-3-phenylpropanal 
• 22711-21-3 4-methoxybenzil 
• 1307830-63-2 5-(2-methoxybenzyl)-5-phenylimidazolidine-2,4-dione 
• 1307830-65-4 5-(2-methoxybenzyl)-5-phenyl-2-thioxoimidazolidin-4-one 

Relevant academic research and scientific papers

Practical approach for preparation of unsymmetric benzils from β-ketoaldehydes

An efficient and practical method for the synthesis of unsymmetric benzils from readily available β-ketoaldehydes has been developed. Various unsymmetric 1,2-diaryldiketones bearing functional groups have been obtained in good to excellent yields under mild reaction conditions. A plausible mechanism was proposed, and α,α-dichloroketone was considered as the key intermediate. The generation of α,α-dichloroketones from β-ketoaldehydes may undergo the following steps: (1) oxidation by sodium hypochlorite, (2) decarboxylation, and (3) chlorination by Cl2 generated from sodium hypochlorite.

Biomimetic hydrogenation: A reusable NADH co-enzyme model for hydrogenation of α,β-epoxy ketones and 1,2-diketones

A biomimetic method has been developed to transform α,β-epoxy ketones or 1,2-diketones into corresponding β-hydroxy ketones or α-hydroxy ketones using a catalytic amount of BNAH or BNA +Br-. The regeneration of BNAH or BNA+Br - is achieved by a mixture of HCOOH/Et3N. A radical mechanism is proposed to explain these observations.

PAA-supported Hantzsch 1,4-dihydropyridine ester: An efficient catalyst for the hydrogenation of α,β-epoxy ketones

A new type of water-soluble polymer-supported NADH co-enzyme model-PAA (polyacrylic acid)-supported Hantzsch 1,4-dihydropyridine ester (PAA-HEH) was designed and synthesized. Catalytic amount of the supported reagent was used in the hydrogenation of α,β-epoxy ketones to the corresponding β-hydroxy ketones and showed great catalytic efficiency in the reduction reaction. This PAA-HEH was an optimal potential for recycling use.

Conversion of 2-methoxychalcones into 3-phenylcoumarins

A new approach to the synthesis of 3-phenylcoumarins from 2-methoxychalcone is presented.This conversion constitutes an interesting way of reorganising the central C3-unit of the chalcone.