6840-28-4

Basic information

• Product Name: Phosphine oxide, (4-methylphenyl)diphenyl-
• CAS NO: 6840-28-4
• Molecular Formula: C19H17OP
• Molecular Weight: 292.317
• Mol File: 6840-28-4.mol
• Article Data: 54

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, (4-methylphenyl)diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, (4-methylphenyl)diphenyl-(6840-28-4)
• EPA Substance Registry System: Phosphine oxide, (4-methylphenyl)diphenyl-(6840-28-4)

Safety Data

• Hazardous Substances Data: 6840-28-4(Hazardous Substances Data)

Usage

General Description

Phosphine oxide, (4-methylphenyl)diphenyl- is a chemical compound with the molecular formula C19H17OP. It is a phosphine oxide derivative, which is commonly used in organic synthesis and various industrial applications. Phosphine oxide, (4-methylphenyl)diphenyl- is a colorless to pale yellow solid, and its primary use is as a flame retardant and plasticizer in the production of polymers and resins. It is also utilized in the manufacture of adhesives, sealants, and coatings. Additionally, it can function as an intermediate in the synthesis of pharmaceuticals and agrochemicals, due to its ability to participate in a variety of chemical reactions to form new compounds. Overall, Phosphine oxide, (4-methylphenyl)diphenyl- is an important chemical with numerous applications in different industries.

Upstream product

• 797-70-6 tri(4-methylphenyl)phosphine oxide 
• 591-51-5 phenyllithium 
• 55743-31-2 (1-chlorovinyl)diphenylphosphine oxide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 25862-12-8 bis(4-methylphenyl) selenoxide 
• 791-28-6 Triphenylphosphine oxide 
• 1774-35-2 di(p-tolyl) sulfoxide 
• 7726-95-6 bromine 
• 1031-93-2 diphenyl(p-tolyl)phosphine 
• 7175-54-4 cumyl peroxy radical 
• 2959-74-2 benzyldiphenylphosphine oxide 
• 1809-20-7 diisopropyl hydrogenphosphonate 
• 106-38-7 para-bromotoluene 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 13118-96-2 phenyl-p-tolyl-phosphinic acid 
• 75784-55-3 (p-bromomethylphenyl)diphenylphosphine oxide 
• 80359-65-5 C₁₉H₁₆CsOP 
• 108-91-8 cyclohexylamine 
• 69882-36-6 trans-4-(Diphenylphosphinyl)-4'-methoxy-stilben 
• 2272-04-0 diphenyl[(4-carboxy)phenyl]phosphine oxide 
• 5068-20-2 (4-(hydroxymethyl)phenyl)diphenylphosphine oxide 
• 101630-35-7 (4-(ethoxycarbonyl)phenyl)diphenylphosphine oxide 
• 1031-93-2 diphenyl(p-tolyl)phosphine 
• 75784-56-4 (4-diphenylphosphinyl)-benzyl triphenylphosphonium bromide 
• 75784-58-6 C₃₁H₂₅⁽²⁾HO₂P₂ 
• 75784-57-5 (4-diphenylphosphinyl)-benzyl diphenylphosphine oxide 
• 63403-56-5 1-(4-dimethylaminophenyl)-2-(4-diphenylphosphinoylphenyl)ethene 
• 905954-22-5 2-[4-(diphenyl-phosphinoyl)-benzyl]-2-ethyl-malonic acid diethyl ester 

Relevant articles and documents

Palladium anchored on a covalent organic framework as a heterogeneous catalyst for phosphorylation of aryl bromides

A simple azine-linked covalent organic framework (COF) with high thermal and chemical stabilities has been prepared by using deep eutectic solvent (DES) as green media. The as-synthesized COF was employed as heterogeneous ligand for immobilization of PdII. The obtained Pd-supported COF nanoparticles catalyst (defined as Pd/TFPT-Azine-COF) was found to be an efficient heterogeneous catalyst for the Hirao reaction of aryl halides and dialkyl phosphites or diphenylphosphine oxide with excellent recyclability, reusability, and retention of crystallinity.

Method for synthesizing trisubstituted arylphosphine oxide species by using diphenyl(tert-butyl)phosphine as substrate

The invention relates to a method for synthesizing a trisubstituted arylphosphine oxide species by taking diphenyl(tert-butyl)phosphine as a substrate, belonging to the technical field of organic phosphine synthesis. The method comprises the following steps: with a transition metal palladium salt as a catalyst and a hydrazine compound and diphenyl(tert-butyl)phosphine as reaction substrates, adding the reaction substrates and an alkali compound into a reaction solvent, carrying out stirring and heating, conducting reacting for a certain period of time to obtain a reaction solution, and separating and purifying the reaction solution to obtain a trisubstituted arylphosphine oxide compound, wherein the hydrazine compound is any one selected from aromatic hydrazine and aromatic heterocyclic hydrazine; and the transition metal palladium salt catalyst is selected from any one of Pd(OAc)2, Pd(dba)2 and PdCl2. Compared with a traditional synthesis method, the method has the advantages that the use of diarylphosphine oxide hydrogen is avoided, raw materials are easy to obtain, reaction conditions are mild, yield is high, and reaction selectivity is good. In general, the method is friendly to environment and simple in synthesis process, and has certain industrial application prospects.

Efficient potassium hydroxide promoted P-arylation of aryl halides with diphenylphosphine

A simple synthetic method of triarylphosphine compounds by KOH-promoted P-Arylation reaction of aryl halides with diphenylphosphine is presented. Notably, this transformation could smoothly proceed with high yields under transition-metal-free and mild reaction conditions. In addition, this protocol is valuable for industrial application due to the convenient operation and readily accessible aromatic halides. A possible explanation of the reaction mechanism was proposed based on the experimental data.