68800-26-0Relevant articles and documents
SYNTHESIS OF ENKEPHALINS BY THE METHOD OF POLYMERIC ACTIVATED ESTERS BASED ON 4-HYDROXY-3-NITROBENZOPHENONE
Grigor'ev, E. I.,Chernova, S. V.
, p. 468 - 474 (2007/10/02)
Leucine- and methionine-enkephalins have been synthesized by the successive growth of the peptide chain from the C-end by the method of polymeric activated esters based on 4-hydroxy-3-nitrobenzophenone with yields of 90 and 70percent, respectively, calculated on the initial C-terminal amino acid.Polystyrene with 2percent of divinylbenzene was used as the polymeric matrix.Using the synthesis of methionine-enkephalin as an example, the possibility has been shown of using polymeric activated esters for the synthesis of peptides with a free carboxy group.
Synthesis of linear and cyclic peptides related to Met- and Leu-enkephalin
Van Nispen,Greven
, p. 451 - 455 (2007/10/02)
-