6940-81-4

Basic information

• Product Name: 2-BENZYLAMINO-PROPAN-1-OL
• Synonyms: 2-BENZYLAMINO-PROPAN-1-OL;DL-2-BENZYLAMINO-1-PROPANOL;ASINEX-REAG BAS 01478558;TIMTEC-BB SBB010465;2-(Benzylamino)-1-propanol;1-Propanol, dl-2-benzylamino-,;N-Benzyl-2-aMinopropanol;DL-2-BENZYLAMINO-1-PROPANOL, AldrichCPR
• CAS NO: 6940-81-4
• Molecular Formula: C10H15NO
• Molecular Weight: 165.23
• Product Categories: pharmacetical
• Mol File: 6940-81-4.mol
• Article Data: 39

Chemical Properties

• Boiling Point: 292.2 °C at 760 mmHg
• Flash Point: 119.9 °C
• Appearance: /
• Density: 1.02 g/cm³
• Vapor Pressure: 0.000848mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 2-BENZYLAMINO-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLAMINO-PROPAN-1-OL(6940-81-4)
• EPA Substance Registry System: 2-BENZYLAMINO-PROPAN-1-OL(6940-81-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 6940-81-4(Hazardous Substances Data)

Usage

General Description

2-Benzylamino-propan-1-ol is a chemical compound with the formula C10H15NO. It is a secondary amine and an alcohol due to the presence of an amino group and a hydroxyl group in its structure. 2-Benzylamino-propan-1-ol is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It is also used in the production of surfactants, detergents, and other industrial applications. 2-Benzylamino-propan-1-ol can be synthesized through various methods and is known for its versatile properties in chemical synthesis and industry.

InChI:InChI=1/C10H15NO/c1-9(8-12)11-7-10-5-3-2-4-6-10/h2-6,9,11-12H,7-8H2,1H3

Upstream product

• 6168-72-5 2-Amino-1-propanol 
• 100-39-0 benzyl bromide 
• 35320-23-1 (R)-2-aminopropan-1-ol 
• 100-52-7 benzaldehyde 
• 2749-11-3 (S)-Alaninol 
• 56-41-7 L-alanin 
• 52724-28-4 bis(tetraethylammonium) carbonate 
• 458560-71-9 (S)-3-benzyl-4-methyl-[1,2,3]-oxathiazolidine-2,2-dioxide 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 98-88-4 benzoyl chloride 
• 7585-47-9 N-benzylalanine 
• 65943-49-9 (S)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propan-1-ol 
• 7244-67-9 N-benzoyl-L-alanine methyl ester 
• 7585-47-9 N-benzyl-(S)-alanine 

Downstream Products

• 122764-74-3 6-methyl-9,10-didehydro-ergoline-8β-carboxylic acid-[benzyl-((S)-β-hydroxy-isopropyl)-amide] 
• 74609-49-7 (2R)-2-[(phenylmethyl)amino]-1-propanol 
• 911792-37-5 4-benzyl-5-methylmorpholin-2-one 
• 118460-11-0 (S)-4-benzyl-5-methylmorpholin-2-one 
• 172034-96-7 2-{[Benzyl-((S)-2-hydroxy-1-methyl-ethyl)-amino]-methyl}-acrylic acid ethyl ester 

Relevant articles and documents

Anchored Palladium Complex-Generated Clusters on Zirconia: Efficiency in Reductive N-Alkylation of Amines with Carbonyl Compounds under Hydrogen Atmosphere

Carbon-nitrogen bond formation is an important method on both laboratory and industrial scales because it realizes the production of valuable pharmaceuticals, agrochemicals, and fine chemicals. Direct reductive N-alkylation of amines with carbonyl compounds via intermediary imine compounds, especially under catalytic hydrogenation conditions, is one of the most convenient, economical, and environmentally friendly methods for this process. Here we report a novel palladium species on zirconia having specific activity towards hydrogenation of imines but other carbonyl groups remaining intact. The present catalytic property offers a practical synthetic method of functionalized secondary amines by reductive N-alkylation under mild conditions with high atom-efficiency. Mechanistic studies revealed that the catalytically active species is the palladium cluster, which is generated in situ from molecular palladium complexes on the support by exposure to atmospheric hydrogen. These fundamental findings are expected to progress in developing novel cluster catalysts for chemical processes directed towards a sustainable society.

6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE AND 6,7-DIHYDRO-4H-TRIAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES

The present invention relates to compounds of the formula (I), or pharmaceutically acceptable salts, enantiomer or diastereomer thereof, wherein R1 to R4 and Q are as described above. The compounds may be useful for the treatment or prophylaxis of hepatitis B virus infection.

Substrate-Controlled Diastereoselectivity Reversal in NHC-Catalyzed Cross-Benzoin Reactions Using N-Boc-N-Bn-Protected α-Amino Aldehydes

The effectiveness of utilizing N-Bn-N-Boc-α-amino aldehydes in cross-benzoin reactions with heteroaromatic aldehydes is demonstrated. The reaction is both chemoselective and syn-selective, making it complementary to the anti-selective cross-benzoin reaction of NHBoc-α-amino aldehydes. Good diastereoselectivity is obtained for a variety of amino aldehydes, including nonhindered ones. A Felkin-Anh model can be used to rationalize the observed diastereoselectivity.