6956-85-0

Basic information

• Product Name: methyl (2-chlorophenoxy)acetate
• CAS NO: 6956-85-0
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.619
• Mol File: 6956-85-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 264.5°C at 760 mmHg
• Flash Point: 109.6°C
• Density: 1.239g/cm³
• Vapor Pressure: 0.00966mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: methyl (2-chlorophenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2-chlorophenoxy)acetate(6956-85-0)
• EPA Substance Registry System: methyl (2-chlorophenoxy)acetate(6956-85-0)

Safety Data

• Hazardous Substances Data: 6956-85-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 614-61-9 (2-chlorophenoxy)acetic acid 
• 95-57-8 2-monochlorophenol 
• 96-32-2 bromoacetic acid methyl ester 
• 96-34-4 methyl chloroacetate 
• 96-35-5 glycolic acid methyl ester 
• 95-50-1 1,2-dichloro-benzene 
• 20143-41-3 (2-chloro-phenoxy)-acetyl chloride 

Downstream Products

• 303014-12-2 [4-(1-benzenesulfonylamino-2,2,2-trichloro-ethyl)-2-chloro-phenoxy]-acetic acid methyl ester 
• 449811-13-6 6-(2-chlorophenoxy)-8-methyl-2-(methylthio)-pyrido[2,3-d]pyrimidin-7(8H)-one 
• 614-61-9 (2-chlorophenoxy)acetic acid 
• 35370-94-6 2-(2-chloro-phenoxy)-thioacetamide 
• 131866-18-7 N,N'-bis-[(2-chloro-phenoxy)-acetyl]-hydrazine 
• 36304-40-2 (2-chlorophenoxy)acetic acid hydrazide 

Relevant articles and documents

Synthesis and herbicidal activities of aryloxyacetic acid derivatives as HPPD inhibitors

A series of aryloxyacetic acid derivatives were designed and synthesized as 4-hydoxyphenylpyruvate dioxygenase (HPPD) inhibitors. Preliminary bioassay results reveal that these derivatives are promising Arabidopsis thaliana HPPD (AtHPPD) inhibitors, in particular compounds I12 (Ki = 0.011 μM) and I23 (Ki = 0.012 μM), which exhibit similar activities to that of mesotrione, a commercial HPPD herbicide (Ki = 0.013 μM). Furthermore, the newly synthesized compounds show significant greenhouse herbicidal activities against tested weeds at dosages of 150 g ai/ha. In particular, II4 exhibited high herbicidal activity for pre-emergence treatment that was slightly better than that of mesotrione. In addition, compound II4 was safe for weed control in maize fields at a rate of 150 g ai/ha, and was identified as the most potent candidate for a novel HPPD inhibitor herbicide. The compounds described herein may provide useful guidance for the design of new HPPD inhibiting herbicides and their modification.

Preparation method of chlorophenoxyacetic ester

The invention provides a preparation method of chlorophenoxyacetic ester, wherein the preparation method comprises the following steps: A) carrying out reaction of glycolic acid and alcohol in tolueneto obtain glycolic ester; B) carrying out reaction of glycolic ester and metal alkoxide to obtain a metal salt of glycolic ester; and C) carrying out reaction of the metal salt of glycolic ester andchlorobenzene to obtain the chlorophenoxyacetic ester. The chlorophenoxyacetic ester is synthesized by condensation of chlorobenzene with the metal salt of glycolic ester, the use of chlorophenol withunpleasant odor is effectively avoided, the production of highly toxic dioxins is eliminated, and the product quality and the operating environment of the production site are greatly improved. Motherliquor containing effective ingredients cannot be produced, so the loss of effective ingredients is effectively avoided and the yield of the product is improved.

A rapid and high-yield synthesis of aryloxyacetyl hydrazides under microwave irradiation and with phase transfer catalysis

A series of aryloxyacetyl hydrazides 4a-l were synthesised under microwave irradiation and phase transfer catalysis conditions. By the optimisation of the reaction conditions, a rapid, high-yield and efficient method for the preparation of aryloxyacety hydrazide was given.