696-57-1

Basic information

• Product Name: N-ALLYLMORPHOLINE
• Synonyms: ALLYLMORPHOLINE;N-ALLYLMORPHOLINE;4-Allylmorpholine;Morpholine, 4-(2-propenyl)-;Morpholine, 4-allyl-;N-Allymorpholine;3-Morpholino-1-propene;4-(2-Propenyl)morpholine
• CAS NO: 696-57-1
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.18
• Product Categories: monomer
• Mol File: 696-57-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 158 °C
• Flash Point: 42.7 °C
• Appearance: /
• Density: 0.93
• Vapor Pressure: 2.56mmHg at 25°C
• Refractive Index: 1.4570-1.4610
• CAS DataBase Reference: N-ALLYLMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ALLYLMORPHOLINE(696-57-1)
• EPA Substance Registry System: N-ALLYLMORPHOLINE(696-57-1)

Safety Data

• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 696-57-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 103, p. 6863, 1981 DOI: 10.1021/ja00413a014

InChI:InChI=1/C7H13NO/c1-2-3-8-4-6-9-7-5-8/h2H,1,3-7H2

Upstream product

• 845464-92-8 2-(2-allyloxyphenyl)oct-3-yn-2-ol 
• 110-91-8 morpholine 
• 201230-82-2 carbon monoxide 
• 845464-90-6 2-(1-Hydroxy-3-phenyl-2-propynyl)-(2-propenyloxy)benzene 
• 934569-92-3 1-(2-allyloxy-5-methoxyphenyl)-3-phenylprop-2-yn-1-ol 
• 934569-84-3 1-(2-allyloxyphenyl)-1-phenylhept-2-yn-1-ol 
• 73086-81-4 1-allyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt 
• 25070-77-3 allyl morpholine-4-carboxylate 
• 463-49-0 1,2-propanediene 

Downstream Products

• 1344667-71-5 2-allyl-6-methylbenzoic acid 
• 1530-89-8 N-cyanomorpholine 
• 94291-68-6 3-morpholinopropyldimethylmethoxysilane 
• 1442942-19-9 N-{3-[dimethyl(5-phenylfuran-2-yl)silyl]propyl}morpholine 
• 94-66-6 2-allylcyclohexan-1-one 
• 1283629-17-3 4-((3-(1-(3-(trifluoromethyl)phenyl)-1H-indol-3-yl)-4,5-dihydroisoxazol-5-yl)methyl)morpholine 
• 1184350-43-3 1-(2-allylphenyl)morpholine 
• 1135493-45-6 N-[3-(3-morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide 
• 338462-42-3 (2S)-N-(2-benzyloxy-4-pentenoyl)-morpholine 

Relevant articles and documents

Cascade reactions: A new synthesis of 2-benzofuran-2-ylacetamides by sequential Pd(0)-catalyzed deallylation-Pd(II)-catalyzed aminocarbonylative heterocyclization of 1-(2-allyloxyaryl)-2-yn-1-ols

(Chemical Equation Presented) A general and efficient synthesis of 2-benzofuran-2-ylacetamides 5 starting from 1-(2-allyloxyaryl)-2-yn-l-ols 1, amines 4, and CO, in the presence of catalytic amounts of PdI2 in conjunction with PPh3 and KI, has been developed based on the "sequential homobimetallic catalysis" concept, that is, a process in which two different complexes of the same metal, but in two different oxidation states, promote two catalytic cycles in sequence. The first cycle corresponds to a Pd(0)-catalyzed aminodeallylation of 1 with formation of the free phenol 2, which then undergoes Pd(II)-catalyzed aminocarbonylative heterocyclization to give the final product 5.

Practical palladium-mediated deprotective method of allyloxycarbonyl in aqueous media

The Allyloxycarbonyl (Alloc) moiety can be removed smoothly and selectively in good yield (73-100%) from allylic esters, carbamates and carbonates by aqueous Pd (O) catalysed allyl transfer to diethylamine in aqueous media employing a water soluble phosphine. The allyl scavenger as well as by product allyl diethylamine are volatile and easily removed in vacuo. In a two phase system an increased selectivity is seen. The method has been successfully used for deprotection of a wide range of secondary amines or base sensitive derivatives and the catalyst is efficiently recycled.

AMINATION OF DIENE HYDROCARBONS. 1. PREPARATION OF N-(2,3-DIMETHYLENEBUTYL)MORPHOLINE BY TELOMERIZATION OF PROPANE

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