69674-27-7

Basic information

• Product Name: 6-bromo-4-methylquinazoline
• Synonyms: 6-bromo-4-methylquinazoline
• CAS NO: 69674-27-7
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.0693
• Mol File: 69674-27-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 320.098 °C at 760 mmHg
• Flash Point: 147.39 °C
• Appearance: /
• Density: 1.566 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 6-bromo-4-methylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-4-methylquinazoline(69674-27-7)
• EPA Substance Registry System: 6-bromo-4-methylquinazoline(69674-27-7)

Safety Data

• Hazardous Substances Data: 69674-27-7(Hazardous Substances Data)

Usage

General Description

6-Bromo-4-methylquinazoline is a chemical compound that belongs to the quinazoline class of molecules. It is a heterocyclic compound with a bromine atom at position 6 and a methyl group at position 4. Quinazoline derivatives have been studied for their potential pharmaceutical applications, including as antiviral, anticancer, and anti-inflammatory agents. This specific compound may have potential uses in medicinal chemistry and drug development due to its unique structural features and potential biological activities. Additionally, quinazoline derivatives have also been investigated for their use as fluorescent probes and in the synthesis of various organic compounds.

InChI:InChI=1/C9H7BrN2/c1-6-8-4-7(10)2-3-9(8)12-5-11-6/h2-5H,1H3

Upstream product

• 29124-56-9 1-(2-amino-5-bromophenyl)ethanone 
• 122-51-0 orthoformic acid triethyl ester 
• 551-93-9 2-aminoacetophenone 
• 463-52-5 formamidine 
• 631-61-8 ammonium acetate 

Downstream Products

• 769916-07-6 C₉H₅BrN₂O₂ 
• 474710-78-6 methyl 6-bromoquinazolin-4-carboxylate 

Relevant articles and documents

SUBSTITUTED ARYL COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF

The present application relates to a substituted aryl compound or a pharmaceutically acceptable salt, a stereoisomer, a polymorph, a solvate, a N-oxide, an isotope-labeled compound, a metabolite or a prodrug thereof, and a preparation method therefor and use thereof, also relates to a pharmaceutical composition containing the compound and a therapeutic use thereof. The compound or a pharmaceutical composition thereof can inhibit the activity of adenosine A2a receptor, and can be used for treating or preventing a disease related to adenosine A2a receptor, especially for treating a tumor.

Substituted pyrazine compound as well as preparation method and application thereof

The invention discloses a substituted pyrazine compound as an adenosine receptor antagonist, a preparation method and an intermediate thereof, a pharmaceutical composition containing the substituted pyrazine compound, and a therapeutic application of the

2-amino pyrimidine derivative, preparation method thereof and application thereof in medicine

The invention relates to 2-amino pyrimidine derivative, a preparation method thereof and an application thereof in medicine. In particular, the present invention relates to a 2-amino pyrimidine derivative shown in the general formula (I), a preparation method thereof, a pharmaceutical composition containing that derivative and use thereof as therapeutic agent, in particular as an A2a receptor and/or A2b receptor antagonist and in the preparation of a drug for the treatment of a condition or disorder improved by inhibition of the A2a receptor and/or A2b receptor, wherein the substituents of thegeneral formula (I) are the same as defined in the specification.