70200-14-5

Basic information

• Product Name: ethyl 3-hydroxy-3-(4-chlorophenyl)propanoate
• Synonyms: ethyl 3-hydroxy-3-(4-chlorophenyl)propanoate
• CAS NO: 70200-14-5
• Molecular Weight: 228.675
• Mol File: 70200-14-5.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: ethyl 3-hydroxy-3-(4-chlorophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-hydroxy-3-(4-chlorophenyl)propanoate(70200-14-5)
• EPA Substance Registry System: ethyl 3-hydroxy-3-(4-chlorophenyl)propanoate(70200-14-5)

Safety Data

• Hazardous Substances Data: 70200-14-5(Hazardous Substances Data)

Upstream product

• 1600-27-7 mercury(II) diacetate 
• 104-88-1 4-chlorobenzaldehyde 
• 927-80-0 1-ethoxyacetylene 
• 105-39-5 chloroacetic acid ethyl ester 
• 64-17-5 ethanol 
• 22027-53-8 methyl 3-(4-chlorophenyl)-3-oxopropanoate 
• 99-91-2 para-chloroacetophenone 
• 623-48-3 ethyl iodoacetae 
• 2881-63-2 ethyl (4-chlorobenzoyl)acetate 
• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 
• 141-78-6 ethyl acetate 
• 105-36-2 ethyl bromoacetate 
• 123843-32-3 carbethoxymethyltri-n-butylstibonium tetraphenylborate 

Downstream Products

• 24393-52-0 ethyl (E)-3-(4-chlorophenyl)prop-2-enoate 
• 1351766-96-5 (S)-1-(4-chlorophenyl)-3-ethoxy-3-oxopropyl decanoate 
• 1351766-66-9 (R)-1-(4-chlorophenyl)-3-ethoxy-3-oxopropyl decanoate 
• 141545-22-4 (R)-3-hydroxy-3-(4-chlorophenyl)-propionic acid ethyl ester 
• 1351766-82-9 1-(4-chlorophenyl)-3-ethoxy-3-oxopropyl decanoate 
• 910135-66-9 C₁₆H₁₆ClN₃O₂S 
• 910135-63-6 C₁₂H₁₆ClN₃O₂S 
• 928780-22-7 4-amino-1-{3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-[4-(4-chloro-phenyl)-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yloxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidin-2-one 
• 537676-63-4 ethyl (3R)-3-cyano-3-(4-chlorophenyl)propanoate 
• 537676-65-6 ethyl (3S)-3-bromo-3-(4-chlorophenyl)propanoate 
• 299179-24-1 ethyl (2S,3R)-3-(4-chlorophenyl)-2,3-dihydroxypropionate 
• 1006386-90-8 ethyl (2R,3S)-3-(4-chlorophenyl)-2,3-dihydroxypropionate 
• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 123632-31-5 (S)-(+)-4-(4-chlorophenyl)pyrrolidin-2-one 

Relevant articles and documents

A practical method for the Reformatsky reaction of aldehydes

Reformaksky reaction of aliphatic aldehydes has been performed successfully by the addition of BF3·OEt2 to a stirred suspension of aldehyde, bromo ester and Zn dust in aqueous THF. For aromatic aldehydes, addition of benzoyl peroxide is also required to effect the reaction.

Method for preparing β - hydroxyl carbonyl compound (by machine translation)

The present invention relates to a process for preparing β - hydroxycarbonyl compounds, which mainly provides a process for the reaction, using inexpensive commercial iron powder-mediated α -halocarbonyl compounds with aldehydes/ketones, to provide the corresponding β - hydroxycarbonyl compound . the present invention relates to a method. The process is good, has wide functional group tolerance and good compatibility. (by machine translation)

A Ball-Milling-Enabled Reformatsky Reaction

An operationally simple one-jar one-step mechanochemical Reformatsky reaction using in situ generated organozinc intermediates under neat grinding conditions has been developed. Notable features of this reaction protocol are that it requires no solvent, no inert gases, and no pre-activation of the bulk zinc source. The developed process is demonstrated to have good substrate scope (39–82 % yield) and is effective irrespective of the initial morphology of the zinc source.