703-66-2 Usage
Uses
Used in Pharmaceutical Industry:
6,8-Dichloroquinoline is used as a medicinal compound for its pharmaceutical applications. Its medicinal properties make it a valuable component in the development of various drugs and treatments.
Used in Chemical Research:
6,8-Dichloroquinoline is used as a research chemical for studying the properties and reactions of quinolines and their derivatives. This helps in understanding their potential applications and developing new compounds with desired characteristics.
Used in Agricultural Applications:
6,8-Dichloroquinoline is used as a chemical intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its presence in these products can contribute to their effectiveness in controlling pests and weeds.
Used in Industrial Applications:
6,8-Dichloroquinoline is used as a raw material in the production of various industrial chemicals and materials. Its versatility in chemical reactions allows for the creation of a wide range of products with specific properties and applications.
Environmental Considerations:
Due to the chlorinated structure of 6,8-dichlorquinoline, it is important to consider its potential environmental impact. It is used with caution and under professional supervision to minimize the risks associated with its disposal and potential contamination of soil, water, and air. Proper handling and disposal methods are essential to ensure the safety of the environment and human health.
Check Digit Verification of cas no
The CAS Registry Mumber 703-66-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 703-66:
(5*7)+(4*0)+(3*3)+(2*6)+(1*6)=62
62 % 10 = 2
So 703-66-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H5Cl2N/c10-7-4-6-2-1-3-12-9(6)8(11)5-7/h1-5H
703-66-2Relevant academic research and scientific papers
DMSO/t-BuONa/O2-Mediated Aerobic Dehydrogenation of Saturated N-Heterocycles
Cai, Hu,Tan, Wei,Xie, Yongfa,Yang, Ruchun,Yue, Shusheng
, p. 7501 - 7509 (2020/07/07)
Aromatic N-heterocycles such as quinolines, isoquinolines, and indolines are synthesized via sodium tert-butoxide-promoted oxidative dehydrogenation of the saturated heterocycles in DMSO solution. This reaction proceeds under mild reaction conditions and has a good functional group tolerance. Mechanistic studies suggest a radical pathway involving hydrogen abstraction of dimsyl radicals from the N-H bond or α-C-H of the substrates and subsequent oxidation of the nitrogen or α-aminoalkyl radicals.
From Anilines to Quinolines: Iodide- and Silver-Mediated Aerobic Double C?H Oxidative Annulation–Aromatization
Wu, Jiwei,Liao, Zhixiong,Liu, Dong,Chiang, Chien-Wei,Li, Zheng,Zhou, Zhonghao,Yi, Hong,Zhang, Xu,Deng, Zixin,Lei, Aiwen
supporting information, p. 15874 - 15878 (2017/10/23)
Quinoline synthesis from easily accessible raw materials such as anilines is a valuable and meaningful task. Herein, we communicate an iodide- and silver-mediated C?H/C?H oxidative annulation–aromatization between anilines and allyl alcohols. This protocol provides a direct route to the synthesis of quinoline derivatives from inexpensive commodities. Various kinds of anilines, even heterocyclic anilines, were shown to be workable substrates, generating the corresponding multi-substituted quinolines in good yields.
