7039-50-1

Basic information

• Product Name: 2-amino-5-chloro-diphenyl methanol
• Synonyms: 2-amino-5-chloro-diphenyl methanol;2-Amino-5-chlorobenzhydrol;(2-Amino-5-chlorophenyl)(phenyl)methanol, 4-Chloro-2-[hydroxy(phenyl)methyl]aniline
• CAS NO: 7039-50-1
• Molecular Formula: C13H12ClNO
• Molecular Weight: 233.7
• Mol File: 7039-50-1.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-5-chloro-diphenyl methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-chloro-diphenyl methanol(7039-50-1)
• EPA Substance Registry System: 2-amino-5-chloro-diphenyl methanol(7039-50-1)

Safety Data

• Hazardous Substances Data: 7039-50-1(Hazardous Substances Data)

Usage

General Description

2-amino-5-chloro-diphenyl methanol is a chemical compound that belongs to the class of phenylalanine derivatives. It is a white crystalline powder with a molecular formula C13H12ClNO and a molecular weight of 239.69 g/mol. 2-amino-5-chloro-diphenyl methanol is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has been studied for its potential applications in treating various diseases, including cancer and infectious diseases. Additionally, 2-amino-5-chloro-diphenyl methanol has also been investigated for its antibacterial and antifungal properties, making it a versatile and potentially valuable chemical in the field of medicinal chemistry.

Upstream product

• 100-52-7 benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 1159372-20-9 (2-amino-5-chlorophenyl)(phenyl)methanol 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 6628-86-0 5-chloro-2-nitrobenzaldehyde 
• 20028-53-9 2-amino-5-chlorobenzaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 60794-27-6 (5-chloro-2-nitro-phenyl)-phenyl-methanol 

Downstream Products

• 1171122-81-8 Br^(1-)*C₃₁H₂₆ClNP⁽¹⁺⁾ 
• 30169-34-7 6-chloro-2,4-diphenyl-quinazoline 
• 4015-28-5 6-chloro-4-phenylquinazoline 
• 13386-34-0 6-chloro-1-[3-(4-methyl-piperazin-1-yl)-propyl]-4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 13213-92-8 6-chloro-1-(4-chloro-benzoyl)-4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 13213-97-3 6-chloro-1-(2-diethylamino-ethyl)-4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 13213-93-9 1-benzoyl-6-chloro-4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 132735-20-7 6-Chloro-2-ethylthio-3,4-diphenyl-3H-3,4-dihydroquinazoline hydroiodide 
• 132735-17-2 6-Chloro-2-ethylthio-4-phenyl-1H-3,4-dihydroquinazoline hydroiodide 
• 120075-95-8 6-Chloro-2-methylthio-4-phenyl-1H-3,4-dihydroquinazoline hydroiodide 
• 64820-66-2 6-chloro-4-phenyl-3,4-dihydro-1H-quinazolin-2-one 
• 82562-66-1 2-(6-Chloro-4-phenyl-4H-benzo[d][1,3]oxazin-2-yl)-phenol 

Relevant articles and documents

Facile Access to Triazole-Fused 3,1-Benzoxazines Enabled by Metal-Free Base-Promoted Intramolecular C-O Coupling

A convenient approach to assemble 1,2,3-triazole-fused 4 H -3,1-benzoxazines has been developed. Diverse alcohol-tethered 5-iodotriazoles, readily accessible by a modified protocol of Cu-catalyzed (3+2)-cycloaddition, were utilized as precursors of the target fused heterocycles. The intramolecular C-O coupling proceeded efficiently under base-mediated transition-metal-free conditions, furnishing cyclization products in yields up to 96%. Suppression of the competing reductive cleavage of the C-I bond was achieved by the use of Na 2CO 3in acetonitrile at 100 °C. This practical and cost-effective procedure features a broad substrate scope and valuable functional group tolerance.

An efficient iron-promoted synthesis of 6H-indolo[2,3- b] quinolines and neocryptolepine derivatives

A facile and practical method for the preparation of 6H-indolo[2,3-b]quinolines and neocryptolepines was developed under the promotion of the easily available ferric trichloride, affording the desired products with moderate to good yields.

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.