70489-49-5Relevant academic research and scientific papers
A total synthesis and structural aspects of racemic 8-oxygenated tetracyclines
Glatz,Helmchen,Muxfeldt,et al.
, p. 2171 - 2181 (1979)
A stereoselective total synthesis of the first 8-oxygenated tetracycline derivatives 43 and 4 is described. Key steps for the construction of the tetracycline skeleton are the condensation of the tetralone aldehyde 24 with the thiazolone 32 followed by co
