Journal of the American Chemical Society p. 2171 - 2181 (1979)
Update date:2022-07-30
Topics:
Glatz
Helmchen
Muxfeldt
et al.
A stereoselective total synthesis of the first 8-oxygenated tetracycline derivatives 43 and 4 is described. Key steps for the construction of the tetracycline skeleton are the condensation of the tetralone aldehyde 24 with the thiazolone 32 followed by co
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