708-53-2

Usage

Preparation

Preparation by reaction of acetic acid on pyrogallol 1-methyl ether, ? with zinc chloride at reflux (155–160°) (Nencki reaction); ? with boron trifluoride on a steam bath (77%).

InChI:InChI=1/C9H10O4/c1-5(10)6-3-4-7(13-2)9(12)8(6)11/h3-4,11-12H,1-2H3

Upstream product

• 5396-18-9 2'-hydroxy-3',4'-dimethoxyacetophenone 
• 934-00-9 3-methocycatechol 
• 944-99-0 acetic acid 2,6-dimethoxy-phenyl ester 
• 7507-97-3 1-(3-ethoxy-2-hydroxy-4-methoxy-phenyl)-ethanone 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 75-36-5 acetyl chloride 
• 528-21-2 2',3',4'-trihydroxyacetophenone 
• 77-78-1 dimethyl sulfate 
• 13909-73-4 2',3',4'-trimethoxyacetophenone 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 7446-70-0 aluminium trichloride 
• 111211-64-4 3-methoxycatechol diacetate 
• 98-95-3 nitrobenzene 
• 64-19-7 acetic acid 

Downstream Products

• 62078-15-3 1-(2,3-diethoxy-4-methoxy-phenyl)-ethanone 
• 40316-76-5 8-Hydroxy-7-methoxyflavone 
• 2038-73-5 3-Methoxy-6-acetyl-benzochinon-(1,2) 
• 7478-81-1 1-(2,3-bis-benzoyloxy-4-methoxy-phenyl)-ethanone 
• 7595-82-6 1-(2,3-diacetoxy-4-methoxy-phenyl)-ethanone 
• 1001056-78-5 C₁₄H₁₈O₄ 
• 105476-19-5 2,3-diethoxy-4-methoxy-benzoic acid 
• 883745-87-7 (3,4-diisopropoxy-5-isopropyl-2-methoxyphenyl)-(2,6,6-trimethylcyclohex-1-enyl)methanol 

Relevant academic research and scientific papers

Total synthesis of bulbophylol-B

The first total synthesis of bulbophylol-B (1) has been achieved with the longest linear sequence of 12 steps and an overall yield of 17.9% via a new and practical approach to construct the dihydrodibenz[b,f]oxepin skeleton employing Wittig, selective reduction, and intramolecular Ullmann reactions as key steps.

SELECTIVE DEMETHYLATIONS IN 2,3,4-TRIMETHOXYARYL CARBONYL COMPOUNDS

2,3,4-Trimethoxybenzaldehyde, -acetophenone and -benzoic acid give the corresponding 2,3-dihydroxy-4-methoxy compounds in good yield on treatment with BCl3.