71022-60-1

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 104-84-7 para-methylbenzylamine 
• 104-85-8 para-methylbenzonitrile 
• 60-29-7 diethyl ether 
• 64-17-5 ethanol 
• 17271-89-5 4-methylphenylmethylazide 
• 124-38-9 carbon dioxide 
• 589-18-4 4-Methylbenzyl alcohol 
• 111-26-2 hexan-1-amine 
• 78-81-9 isobutylamine 
• 55096-86-1 benzyl(4-methylbenzyl)amine 
• 7732-18-5 water 
• 253786-78-6 O-(1-naphthoyl)-N,N-bis(p-methylbenzyl)hydroxylamine 
• 945-51-7 1,1'-sulfinylbisbenzene 

Downstream Products

• 78842-09-8 bis-(4-methyl-benzyl)-amine; hydrochloride 
• 223753-09-1 1,1-bis(3'-indolyl)-1-(p-methylphenyl)methane 
• 1335220-17-1 1-(4-methylbenzyl)-2-p-tolyl-2,3-dihydropyridin-4(1H)-one 
• 428819-02-7 1-(4-methyl-phenyl)-hexa-4,5-dienyl-1-amine 
• 98180-43-9 bis(4-methylbenzyl)amine 
• 617713-92-5 1-(4-methylphenyl)-octa-4,5-dienyl-1-amine 
• 428819-10-7 1-(4-methyl-phenyl)-hepta-5,6-dienyl-1-amine 

Relevant academic research and scientific papers

Rhodium-catalyzed synthesis of quinolines and imines under mild conditions

An environmentally benign protocol for the synthesis of quinolines in aqueous medium by using a Rh(ii)acetate/TPPTS recyclable catalytic system has been developed. Anilines reacted smoothly with allyl alcohols furnishing the corresponding quinolines in moderate to good yields. This catalytic system was recycled up to five runs without much loss in its catalytic activity. Furthermore, imines were also synthesized from benzylamines in moderate to good yields.

Erratum: Metal-free oxidative coupling of arylmethylamines with indoles: A simple, environmentally benign approach for the synthesis of 3,3′-bis(indolyl)methanes (RSC Advances (2020) 10 (23254-23262) DOI: 10.1039/D0RA03221B)

The authors regret several errors throughout this RSC Advances manuscript. These include an incorrect description of ref. 23 (ref. 1) which starts at line 11 of paragraph 3 in the Introduction and should read as: “Previously, the Gopalaiah research group reported the synthesis of 3,30-benzylidenebis(1H-indole), using an iron(II) tri?ate catalyst, from benzylamine with indoles.23” as opposed to “Previously, the Sankala research group reported the synthesis of 3,30-benzylidenebis(1H-indole), using an iron(II) tri?ate catalyst, from benzylamine with indoles.23” The authors regret an error in Scheme 2 where 4-methylbenzylamine was incorrectly labelled as compound 1a and should have been labelled as compound 1b. The correct version of Scheme 2 is shown below. The authors regret the inclusion of the following sentence starting at line 3 of paragraph 1 in the Experimental section: “Iron salts were purchased from Sigma-Aldrich and were used as received.” This sentence should be removed as it does not relate to the experimental procedures in this RSC Advances article. The authors also regret that the wrong temperature was stated in line 4 of paragraph 2 in the Experimental section, it should read as “The round bottom ?ask was equipped with an O2 balloon, and the reaction mixture was stirred at 120C until the complete consumption of indole 2 occurred, as monitored via TLC.” The authors regret that 4-methyl-N-(4-methylbenzylidene)benzylamine was incorrectly described in lines 10 and 11 of paragraph 3 in the Experimental section. 4-Methylbenzylamine was also incorrectly labelled as compound 1a in line 2 and the wrong temperature was stated in line 5. Paragraph 3 in the Experimental section should therefore read as: “4-Methylbenzylamine (1b) (Figure Presented).

Cyclometalated Half-Sandwich Iridium(III) Complexes: Synthesis, Structure, and Diverse Catalytic Activity in Imine Synthesis Using Air as the Oxidant

Four air-stable cyclometalated half-sandwich iridium complexes 1-4 with C,N-donor Schiff base ligands were prepared through C-H activation in moderate-to-good yields. These complexes have been well characterized, and their exact structure was elaborated on by single-crystal X-ray analysis. The iridium(III) complexes 1-4 showed good catalytic activity in the imine synthesis under open-flask conditions (air as the oxidant) from primary amine oxidative homocoupling, secondary amine dehydrogenation, and the cross-coupling reaction of amine and alcohol. Substituents bonded on the ligands of the iridium complexes displayed little effect on the catalytic efficiency. The stability and good catalytic efficiency of the iridium catalysts, mild reaction conditions, and substrate universality showed their potential application in industrial production.

Visible-light-responsive lanthanide coordination polymers for highly efficient photocatalytic aerobic oxidation of amines and thiols

Development of visible-light-induced photocatalytic reactions using molecular oxygen as the terminal oxidant is intriguing in view of the current environmental and energy issues. We report herein the synthesis and characterization of a series of novel pho

Aprotic Amine-modified Manganese Dioxide Catalysts for Selectivity-tunable Oxidation of Amines

Organic modifiers have shown promising potential for regulating the activity and selectivity of heterogeneous catalysts via tuning their surface properties. Despite the increasing application of organic modification technique in regulating the redox-acid

FeCl2-PPh3 as an efficient catalytic system for the acceptorless dehydrogenation of amines into imines

In this work, a novel and simple catalytic system including FeCl2, PPh3 and potassium tert-butoxide has been employed for the synthesis of imines from amines. In order to prove the catalytic acceptorless dehydrogenation pathway for this transformation, the liberated H2 gas is detected by NMR spectroscopy. By utilizing this protocol, a variety of arylamines were used successfully for the preparation of corresponding imines in good to excellent yields (on a 1?mmol scale, 73–91% yield for homocoupling, 71 and 91% for heterocoupling).

Ball-Milling Induced Debonding of Surface Atoms from Metal Bulk for Construing High-Performance Dual-Site Single-Atom Catalysts

One of the most pressing challenges in single-atom catalysis is the manipulation of the coordination environment of central metals to maximize the catalyst performance. Herein, we fabricated a high-performance catalyst (Co-SNC) by introducing S into the n

Fe2Mn(μ3-O)(COO)6 Cluster Based Stable MOF for Oxidative Coupling of Amines via Heterometallic Synergy

The direct catalytic oxidative coupling of amines is one of the attracting methods for the synthesis of a variety of pharmaceutical or industrial needed imines. Numerous earth-abundant manganese based salts, oxides, and complexes have been applied in this reaction. However, these compounds suffered from difficult separation, large catalyst loading, complicated reactivation or indeterminate activity. Considering the facts that metal-organic frameworks (MOFs) with crystalline structure, precise composition, and enormous surface area have superior performance in heterogeneous catalytic reactions, herein, we introduced Mn into [Fe3(μ3-O)(CH3COO)6], one of the precursors for the preparation of stable MOFs, and got [Fe2Mn(μ3-O)(CH3COO)6] cluster. After ligand replacement with biphenyl-3,4’,5-tricarboxylic acid (BPTC), heterometallic cluster-based [Fe2Mn(μ3-O)(BPTC)2(DMF)2(H2O)] (1) was obtained. As expected, 1 is stable and able to catalyze the homo- or cross-coupling of amines effectively and selectively with 0.9 mol% catalyst loading at room temperature. Control experiments indicated that the catalytic activity of 1 mainly stems from Mn sites and that Fe synergistically contributes to the stability. Additionally, 1 is recyclable and can be reused easily for at least 8 runs without obvious decrease in catalytic ability. To our knowledge, 1 should be the first heterometallic cluster-based MOF with defined structure suitable for the synthesis of diverse imines from oxidative coupling of amines under mild conditions, which may shed light on the easy preparation of effective heterogeneous catalysts for organic synthesis.

Covalent-organic frameworks with keto-enol tautomerism for efficient photocatalytic oxidative coupling of amines to imines under visible light

Photocatalytic oxidation of organic molecules into highly value-added products is an innovative and challenging research which has gradually attracted remarkable attention of scientists. In this work, it is demonstrated that the COF-TpPa with keto-enol ta

Direct synthesis of amides and imines by dehydrogenative homo or cross-coupling of amines and alcohols catalyzed by Cu-MOF

Oxidative dehydrogenative homo-coupling of amines to imines and cross-coupling of amines with alcohols to amides was achieved with high to moderate yields at room temperature in THF using Cu-MOF as an efficient and recyclable heterogeneous catalyst under mild conditions. Different primary benzyl amines and alcohols could be utilized for the synthesis of a wide variety of amides and imines. The Cu-MOF catalyst could be recycled and reused four times without loss of catalytic activity.