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7113-02-2

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7113-02-2 Usage

General Description

2-Phenylthiazole-4-carboxylic acid methyl ester is an organic compound with the molecular formula C11H9NO2S. It is a derivative of thiazole, a five-membered aromatic heterocyclic compound containing a sulfur atom and a nitrogen atom. This chemical compound is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and biological activity. It is also used as a building block for the preparation of various chemical compounds and intermediates. Its methyl ester functional group makes it suitable for various chemical reactions and transformations, making it a valuable compound in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 7113-02-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,1 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7113-02:
(6*7)+(5*1)+(4*1)+(3*3)+(2*0)+(1*2)=62
62 % 10 = 2
So 7113-02-2 is a valid CAS Registry Number.

7113-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-phenyl-1,3-thiazole-4-carboxylate

1.2 Other means of identification

Product number -
Other names METHYL 2-PHENYLTHIAZOLE-4-CARBOXYLATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7113-02-2 SDS

7113-02-2Relevant articles and documents

Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics

Hussein, Waleed M.,Feder, Daniel,Schenk, Gerhard,Guddat, Luke W.,McGeary, Ross P.

, p. 462 - 479 (2018/08/21)

Purple acid phosphatases (PAPs) are metalloenzymes that catalyse the hydrolysis of phosphate esters under acidic conditions. Their active site contains a Fe(III)Fe(II) metal centre in mammals and a Fe(III)Zn(II) or Fe(III)Mn(II) metal centre in plants. In humans, elevated PAP levels in serum strongly correlate with the progression of osteoporosis and metabolic bone malignancies, which make PAP a target suitable for the development of chemotherapeutics to combat bone ailments. Due to difficulties in obtaining the human enzyme, the corresponding enzymes from red kidney bean and pig have been used previously to develop specific PAP inhibitors. Here, existing lead compounds were further elaborated to create a series of inhibitors with Ki values as low as ~30 μM. The inhibition constants of these compounds were of comparable magnitude for pig and red kidney bean PAPs, indicating that relevant binding interactions are conserved. The crystal structure of red kidney bean PAP in complex with the most potent inhibitor in this series, compound 4f, was solved to 2.40 ? resolution. This inhibitor coordinates directly to the binuclear metal centre in the active site as expected based on its competitive mode of inhibition. Docking simulations predict that this compound binds to human PAP in a similar mode. This study presents the first example of a PAP structure in complex with an inhibitor that is of relevance to the development of anti-osteoporotic chemotherapeutics.

Concise synthesis of 2,4-disubstituted thiazoles from β-azido disulfides and carboxylic acids or anhydrides: Asymmetric synthesis of cystothiazole C

Liu, Yi,Sun, Xue,Zhang, Xing,Liu, Jun,Du, Yuguo

, p. 8453 - 8461 (2014/12/10)

A novel and efficient method for the one-pot synthesis of 2,4-disubstituted thiazoles from carboxylic acids or anhydrides is presented. Based on this new method, the total synthesis of the bis-2,4-disubstituted bis(thiazoles) natural product cystothiazole C is also presented. This journal is

PAR4 AGONIST PEPTIDES

-

Page/Page column, (2013/11/06)

The present invention provides PAR4 agonist peptides. These peptides are useful for developing robust PAR4 receptor assays.

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