71479-08-8Relevant academic research and scientific papers
Mukaiyama aldol reactions catalyzed by a trimeric organo aluminum(III) alkoxide
Kim, So Han,Yoon, Sungwoo,Kim, Youngjo,Verkade, John G.
, p. 1193 - 1206 (2014/09/30)
Mukaiyama aldol reactions of enol ethers with a variety of aldehydes and ketones are efficiently catalyzed at 0-25 °C by the sterically bulky trimeric organo aluminum(III) alkoxide 1 synthesized via the reaction of 3 equiv of AlMe3 with tripodal tris(2-hydroxy-3-tert-butyl-5-methylphenyl) methane and the elimination of 3 equiv of methane. Comparisons of its catalytic properties with the less sterically hindered analogue 2, the more sterically hindered analogue 3, a monomeric aluminum near-analogue 4, and a dimeric alumatrane 5 revealed that 1 possesses superior activity.
REACTIONS OF POLYHALO FUNCTIONAL COMPOUNDS WITH METALS AND ELECTROPHILIC REAGENTS. XVI. CHEMICAL BEHAVIOR OF α,α-DIBROMO KETONES IN THE REFORMATSKII REACTION
Shchepin, V. V.,Gladkova, G. E.,Russkikh, N. Yu.
, p. 902 - 907 (2007/10/02)
Geminal α,α-dibromo ketones react with zinc and carbonyl compounds.Depending on the structures of the reactants, the nature of the solvent, and the reaction conditions, α,β-unsaturated ketones, α,β-epoxy ketones, or α-alkyl-β-diketones or their mixtures are formed.
