715-39-9

Upstream product

• 186581-53-3 diazomethane 
• 30448-89-6 3-chloro-4,6-dihydroxy-2-methylbenzoic acid 
• 67-56-1 methanol 
• 101922-80-9 melleolide D 
• 520-43-4 2-hydroxy-4-methoxy-6-methyl-benzoic acid methyl ester 
• 711-47-7 chloro-3-dihydroxy-4,6-methyl-2-benzoate de methyle 
• 77-78-1 dimethyl sulfate 
• 3187-58-4 methyl orsellinate 

Downstream Products

• 99421-09-7 3-chloro-6-hydroxy-4-methoxy-2-methyl-5-nitro-benzoic acid methyl ester 
• 39818-06-9 acide chloro-3-hydroxy-6-methoxy-4-methyl-2-benzoique 
• 78135-48-5 benzyloxy-5-chloro-2-methoxy-3-toluene 
• 78135-54-3 dichloro-3,3'-trihydroxy-4,6,6'-methoxy-4'-dimethyl-2,2'-benzophenone 
• 98968-82-2 tris(benzyloxy)-4,6,6'-dichloro-3,3'-methoxy-4'-dimethyl-2,2'-benzophenone 
• 69709-92-8 3,5,5'-trichloro-2,2'-dihydroxy-4,4'-dimethoxy-6,6'-dimethylbenzophenone 
• 78135-40-7 2,2',4-tribenzyloxy-3,5,5'-trichloro-4'-methoxy-6,6'-dimethylbenzophenone 

Relevant academic research and scientific papers

2,2,6,6-Tetramethylpiperidine-catalyzed, ortho-selective chlorination of phenols by sulfuryl chloride

2,2,6,6-Tetramethylpiperidine (TMP)-catalyzed (1- 10%) chlorinations of phenols by SO2Cl2 in aromatic solvents are more ortho selective than with primary and less hindered secondary amine catalysts. Ortho-selective chlorination is successful even with electron deficient phenols such as 2-hydroxybenzaldehyde and 2'- hydroxyacetophenone. Notably, ortho selectivity increases with the reaction temperature. On the other hand, tetraalkylammonium chloride-catalyzed chlorinations are moderately para selective.

Total synthesis of graphislactone G

We present a total synthesis of the fungal natural product graphislactone G, a chlorinated resorcylic lactone. The key step is a Suzuki coupling used for the construction of the central biaryl bond. Graphislactone G was prepared in 13 steps with 22% yield

STRUCTURES OF MELLEOLIDES B-D, THREE ANTIBACTERIAL SESQUITERPENOIDS FROM ARMILLARIA MELLEA

Key Word Index-Armillaria mellea; Basidiomycete; secondary metabolites; protoilludane derivatives; structural determination.The structures of melleolides B-D, three new protoilludene sesquiterpenoid O-methylorsellinates isolated from a culture of Armillaria mellea, have been elucidated on the basis of chemical and spectral data.

104. Synthese de l'eriodermine

Synthesis of Eriodermin.The total synthesis of eriodermin (=2,7-dichloro-4-formyl 3-hydroxy-8-methoxy-1,6-dimethyl-11H-dibenzodioxepin-11-one) is described.

Depsidone Synthesis. Part 16. Benzophenone-Grisa-3',5'-diene-2',3-dione-depsidone Interconversion: a New Theory of Depsidone Biosynthesis

The synthesis of a number of grisa-3',5'-diene-2',3-diones by oxidative coupling of substituted 2,2'-dihydroxy-4-methoxybenzophenones is described.The rearrangement of these grisadienediones to depsidones under basic, acidic, and thermal conditions is des