71945-87-4Relevant academic research and scientific papers
Multicomponent synthesis of 3,5-diaryl-2,6-dicyanoanilines under thermal solvent-free conditions
Shaterian, Hamid Reza,Honarmand, Moones,Oveisi, Ali Reza
experimental part, p. 557 - 560 (2011/07/31)
A facile parallel synthesis of 3,5-diaryl-2,6-dicyanoanilines via three-component reaction of aryl aldehydes, acetophenone derivatives, and malononitrile under thermal green solvent-free conditions in the presence of potassium carbonate and also potassium bicarbonate without using any hazardous materials is described.
Synthesis of highly substituted 1,6-naphthyridines: A reinvestigation
Veverkova, Eva,Noskova, Marika,Toma, Stefan
, p. 2903 - 2910 (2007/10/03)
A reinvestigation of the recently described method of synthesis of highly substituted 1,6-naphthyridines was carried out. It was found out that the reaction of chalcones with malononitrile catalysed by pyrrolidine afforded the mixture of four products both when thermal as well as microwave heating was used. The claimed[1] 1,6-naphthyridines formation were exceptions.
The reaction of malononitrile with chalcone: A controversial chemical process
Victory, Pedro,Borrell, Jose I.,Vidal-Ferran, Anton,Seoane, Carlos,Soto, Jose L.
, p. 5375 - 5378 (2007/10/02)
Given the significant discrepancies in the several reported results on the reaction of chalcone (1,3-diphenyl-2-propne-1-one) (1) with malononitrile (2), a careful reinvestigation was carried out. Depending upon the reaction conditions either the open-chain Michael adduct (4), an alkoxypyridine (5), an aminoisophthalonitrile (6) or a cyclohexanol (7) is obtained. However, no 4H-pyran could be isolated from this reaction.
α,β-Unsaturated Nitriles in Organic Synthesis: A Novel Synthesis of Biaryls and Azabiaryls
Galil, Fathy M. Abdel,Elnagdi, Mohamed H.
, p. 477 - 480 (2007/10/02)
The reaction of (1-phenylethylidene)malononitrile (2) with cinnamonitrile derivatives 1 a-e afforded the biaryl derivatives 6.The azabiaryls 8 and 10 were synthesized by the reaction of 2 with malononitrile and trichloroacetonitrile.
