72106-01-5Relevant academic research and scientific papers
SUBSTITUTED 4-(1,2,3,4-TETRAHYDROISOQUINOLIN-2-YL)-4-OXORUTYRIC ACID AMIDE AS KCNQ2/3 MODULATORS
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Page/Page column 16-17, (2010/06/22)
The invention relates to substituted tetrahydroisoquinolinyl-4-oxobutyric acid amides, methods for the preparation thereof, medicinal products containing these compounds and the use of these compounds for the preparation of medicinal products
Abnormal products in the Bischler-Napieralski isoquinoline synthesis
Doi, Satoshi,Shirai, Naohiro,Sato, Yoshiro
, p. 2217 - 2221 (2007/10/03)
Reaction of N-[2-(4-methoxyphenyl)ethyl]benzamides with phosphorus pentoxide (and phosphoryl chloride) gives 7-methoxy-1-phenyl-3,4-dihydroisoquinolines (a normal Bischler-Napieralski reaction product) and 6-methoxy-1-phenyl-3,4-dihydroisoquinolines (an abnormal reaction product). The reaction mechanism is discussed.
Synthesis and Molecular Modeling of 1-Phenyl-1,2,3,4-tetrahydroisoquinolines and Related 5,6,8,9-Tetrahydro-13bH-dibenzoquinolizines as D1 Dopamine Antagonists
Minor, Deborah L.,Wyrick, Steven D.,Charifson, Paul S.,Watts, Val J.,Nichols, David E.,Mailman, Richard B.
, p. 4317 - 4328 (2007/10/02)
New 1-phenyl-1,2,3,4-tetrahydroisoquinolines and related 5,6,8,9-tetrahydro-13bH-dibenzo-quinolizines were prepared as ring-contracted analogs of the prototypical 1-phenyl-2,3,4,5-tetrahydrobenzazepines (e.g., SCH23390) as a continuation of our studi
