72223-17-7

Upstream product

• 451-40-1 phenyl benzyl ketone 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 143088-25-9 Selenophosphoric acid O,O'-diisopropyl ester Se-(2-oxo-1,2-diphenyl-ethyl) ester 
• 63578-71-2 Thiophosphoric acid O,O'-diethyl ester S-(2-oxo-1,2-diphenyl-ethyl) ester 
• 118621-73-1 2-(3,4-Dihydroxy-phenyl)-1,2-diphenyl-ethanone 
• 118621-81-1 5-tert-Butyl-2,3-diphenyl-benzofuran-7-ol 
• 118621-80-0 2-(2-tert-Butyl-4,5-dihydroxy-phenyl)-1,2-diphenyl-ethanone 
• 420-56-4 trimethylsilyl fluoride 
• 720-43-4 2-fluoro-1,2-diphenylethanone 
• 41848-64-0 3-bromo-1,2-diphenylpropan-1-one 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 41343-12-8 (Z)-1,3-diphenyl-2-fluoro-2-propen-1-one 
• 108774-24-9 (2S*,3R*)-2,3-diphenylbutan-1-ol 
• 365-01-5 2,2-difluoro-2-phenylacetophenone 
• 4441-01-4 1,2,4-triphenylbutane-1,4-dione 
• 1309976-99-5 C₁₉H₂₁N₃O 

Relevant academic research and scientific papers

Alkyl Ethers as Traceless Hydride Donors in Br?nsted Acid Catalyzed Intramolecular Hydrogen Atom Transfer

A new protocol for the deoxygenation of alcohols and the hydrogenation of alkenes under Br?nsted acid catalysis has been developed. The method is based on the use of either a benzyl or isopropyl ether as a traceless hydrogen-atom donor, and involves an intramolecular hydride transfer as a key step, which is achieved in a regio- and stereoselective manner.

1,4-Silatropy of S-α-silylbenzyl thioesters: A convenient route to silyl enol and dienol ethers accompanied by C-C bond formation via thiocarbonyl ylides

A novel convenient method for the generation of thiocarbonyl ylides from readily accessible starting materials and the first synthetic application of in situ generated ylides in the synthesis of silyl enol and dienol ethers, accompanied by C-C bond formation, is described. Under completely neutral conditions without any catalyst or additive, thermal reactions of S-α-silylbenzyl thioesters in sealed tubes at 180 °C provided silyl enol and dienol ethers in good to excellent yields with high stereoselectivities. This procedure consists of a multistep reaction in a one-pot process, i.e., 1,4-silatropy of S-α-silylbenzyl thioesters to give thiocarbonyl ylides, 1,3-electrocyclization of the ylides to give thiiranes, and the extrusion of sulfur from thiiranes to give silyl enol and dienol ethers.

Carbon-Carbon Bond Formation by the Use of Chloroiodomethane as a C1 Unit. III. A Convenient Synthesis of the Mannich Base from Enol Silyl Ether by a Combination of Chloroiodomethane and N,N,N',N'-Tetramethylmethanediamine

The Mannich dimethylaminomethylation of carbonyl compounds is conveniently carried out via enol trimethylsilyl ethers by a combination of chloroiodomethane (CH2ClI) and N,N,N',N'-tetramethylmethanediamine (TMMD) in DMSO as the solvent at ambient temperatute.The mechanism of the transformation is discussed on the basis of product analysis and 1H NMR spectral studies.The reagent system CH2ClI/TMMD also provides a convenient route to the Eschenmoser's salt ().