72367-10-3

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 

Downstream Products

• 49854-16-2 methyl 2-(2-aminobenzoylamino)benzoate 
• 106274-03-7 2-(2-nitrophenyl)-4H-3,1-benzothiazine-4-thione 
• 7265-24-9 2-(2'-amino-phenyl)-benzo[d][1,3]oxazin-4-one 
• 612-34-0 N-anthraniloyl-anthranilic acid 
• 730970-91-9 N-methyl-N-(2-nitro-benzoyl)-anthranilic acid methyl ester 
• 1616495-21-6 methyl 2-(2-acetamido-N-methylbenzamido)benzoate 
• 54083-72-6 methyl N-methyl-N-(o-aminobenzoyl)anthranilate 
• 2006-80-6 2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoic acid methyl ester 
• 1448441-13-1 (S)-methyl 2-(2-(1-pivaloylpyrrolidine-2-carboxamido)benzamido)benzoate 
• 1129527-34-9 2-{2-[(pyrrolidine-2-carbonyl)-amino]benzoylamino}benzoic acid methyl ester 
• 1448441-19-7 (S)-N-(2-(2-(2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)phenylcarbamoyl)phenylcarbamoyl)phenyl)-1-pivaloylpyrrolidine-2-carboxamide 
• 1448441-20-0 (R)-methyl 2-(2-(2-(2-(pyrrolidine-2-carboxamido)benzamido)benzamido)benzamido)benzoate 
• 1448441-23-3 (R)-tert-butyl 2-{[2-({2-[(2-{[2-(methoxycarbonyl)phenyl]carbamoyl}phenyl)carbamoyl]phenyl}carbamoyl)phenyl]carbamoyl}pyrrolidine-1-carboxylate 
• 1464830-97-4 (S)-2-(2-(2-(2-(1-pivaloylpyrrolidine-2-carboxamido)benzamido)benzamido)benzamido)benzoic acid 

Relevant academic research and scientific papers

Deep eutectic solvent mediated synthesis of quinazolinones and dihydroquinazolinones: Synthesis of natural products and drugs

A mild and greener protocol was developed to synthesize substituted quinazolinones and dihydroquinazolinones via deep eutectic solvent (DES) mediated cyclization with a series of aliphatic, aromatic, and heteroaromatic aldehydes in good to excellent yields. This greener strategy was further utilised to synthesize various quinazolinone natural products and drugs.

Intramolecular metal-free oxidative aryl-aryl coupling: An unusual hypervalent-iodine-mediated rearrangement of 2-substituted n-phenylbenzamides

Hypervalent-iodine-mediated oxidative coupling of the two aryl groups in either 2-acylamino-N-phenyl-benzamides or 2-hydroxy-N-phenylbenzamides, with concomitant insertion of the ortho-substituted N or O atom into the tether, has been described for the first time. This unusual metal-free rearrangement reaction involves an oxidative C(sp2)?C(sp2) aryl-aryl bond formation, cleavage of a C(sp2)?C(O) bond, and a lactamization/lactonization. Furthermore, unsymmetrical diaryl compounds can be easily obtained by removing the tether within the cyclized product.

A synthetic zipper peptide motif orchestrated via co-operative interplay of hydrogen bonding, aromatic stacking, and backbone chirality

Here, we report on a new class of synthetic zipper peptide which assumes its three-dimensional zipper-like structure via a co-operative interplay of hydrogen bonding, aromatic stacking, and backbone chirality. Structural studies carried out in both solid- and solution-state confirmed the zipper-like structural architecture assumed by the synthetic peptide which makes use of unusually remote inter-residual hydrogen-bonding and aromatic stacking interactions to attain its shape. The effect of chirality modulation and the extent of noncovalent forces in the structure stabilization have also been comprehensively explored via single-crystal X-ray diffraction and solution-state NMR studies. The results highlight the utility of noncovalent forces in engineering complex synthetic molecules with intriguing structural architectures.

Oligoanthranilamides. Non-peptide subunits that show formation of specific secondary structure

A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. 1H NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.

Anthranoyl-anthranilic acid: A template for the development of a new class of cholecystokinin receptor ligands

Anthranoyl-anthranilic acid derived from asperlicin as a result of a new disconnection strategy represents a useful template for the development of a new series of non-peptide CCK ligands. The substitution at the N-terminal site of the anthranilic acid di

Synthesis of Heterocyclic Analogs of 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic Acid (Aristolochic Acid)

Analogs of 3,4-methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid (aristolochic acid; 1), namely phenanthridine-1-carboxylic acid (2), 6-carbomethoxy-3,4-methylenedioxyphenanthridine (4) and 1-carbomethoxy-5,6,7,8-tetrahydrophenanthridin-9-ol

Metal Template Reactions. XVII. The Attempted Dimerization of Amino Carbonyl Compounds Containing a Supporting Donor Atom

Attempts to effect metal template condensative dimerizations of the amino aldehydes (4), (11) and (12) and the amino ketone (24) have been unsuccessful.Oxidation of the alcohol (9) did not allow isolation of the aldehyde (4).The alcohol (17) underwent oxi