7237-16-3

Usage

Uses

Used in Polymer Manufacturing:
Phosphonic acid, phenyl-, bis(1-methylethyl) ester is used as a flame retardant and plasticizer for enhancing the safety and flexibility of polymer materials. Its ability to reduce flammability makes it a valuable component in the production of various plastics and resins.
Used in Flame Retardant Applications:
Phosphonic acid, phenyl-, bis(1-methylethyl) ester is used as a flame retardant in the textile, construction, and electronics industries to improve the fire resistance of materials. Its incorporation into products helps to slow down the spread of fire and reduce the risk of damage.
Used in Plasticizer Applications:
In the plastics industry, phosphonic acid, phenyl-, bis(1-methylethyl) ester is used as a plasticizer to increase the flexibility, workability, and durability of plastic materials. This enhances the overall performance and lifespan of plastic products, making them more suitable for various applications.

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 67-63-0 isopropyl alcohol 
• 644-97-3 Dichlorophenylphosphine 
• 20526-22-1 diisopropyl acetylphosphonate 
• 71-43-2 benzene 
• 2388-10-5 lithium isopropoxide 
• 36238-99-0 di(isopropyl) phenylphosphonite 
• 628-37-5 diethyl peroxide 
• 20057-88-9 diphenyl trisulfide 
• 108-86-1 bromobenzene 
• 116-17-6 triisopropyl phosphite 
• 1809-20-7 diisopropyl hydrogenphosphonate 
• 683-60-3 sodium isopropylate 
• 591-50-4 iodobenzene 

Downstream Products

• 51021-91-1 P,P'-diphenyl-P,P'-decane-1,10-diyl-bis-phosphinic acid diisopropyl ester 
• 51021-90-0 P,P'-diphenyl-P,P'-octane-1,8-diyl-bis-phosphinic acid diisopropyl ester 
• 51021-92-2 C₃₀H₄₈O₄P₂ 
• 2307-69-9 toluene-4-sulfonic acid isopropyl ester 
• 134403-63-7 4-benzo-15-crown-5 
• 1571-33-1 phenylphosphonate 
• 7670-94-2 isopropyl hydrogen phenylphosphonate 
• 4297-94-3 monosodium phenylphosphonate 
• 142387-61-9 4-(phenylphosphinoyl)benzo-15-crown-5 
• 51021-83-1 1,10-diphenyl-1,10-diphospha-cyclooctadecane 1r,10t-dioxide 
• 51021-83-1 1,10-diphenyl-1,10-diphospha-cyclooctadecane 1r,10c-dioxide 
• 51021-84-2 1,12-diphenyl-1,12-diphospha-cyclodocosane 1r,12c-dioxide 
• 51021-79-5 1,12-diphenyl-1,12-diphospha-cyclotetracosane 1r,12c-dioxide 
• 51021-82-0 trans-1,12-diphenyl-1,12-diphospha-cyclotetracosane 

Relevant academic research and scientific papers

Selective hydrolysis of phosphorus(v) compounds to form organophosphorus monoacids

An azide and transition metal-free method for the synthesis of elusive phosphonic, phosphinic, and phosphoric monoacids has been developed. Inert pentavalent P(v)-compounds (phosphonate, phosphinate, and phosphate) are activated by triflate anhydride (Tf2O)/pyridine system to form a highly reactive phosphoryl pyridinium intermediate that undergoes nucleophilic substitution with H2O to selectively deprotect one alkoxy group and form organophosphorus monoacids.

Aryltrimethylammonium Tetrafluoroborates in Nickel-Catalyzed C–P Bond-Forming Reactions

Abstract: The first nickel-catalyzed phosphorylation of aryltrimethylammonium tetrafluoroborates with the formation of C–P bond instead of C–N has been developed. Starting from easily available and inexpensive aromatic amines, a variety of important arylphosphonates have been synthesized in moderate to excellent yields.

A case of chain propagation: α-aminoalkyl radicals as initiators for aryl radical chemistry

The generation of aryl radicals from the corresponding halides by redox chemistry is generally considered a difficult task due to their highly negative reduction potentials. Here we demonstrate that α-aminoalkyl radicals can be used as both initiators and chain-carriers for the radical coupling of aryl halides with pyrrole derivatives, a transformation often employed to evaluate new highly reducing photocatalysts. This mode of reactivity obviates for the use of strong reducing species and was also competent in the formation of sp2 C-P bonds. Mechanistic studies have delineated some of the key features operating that trigger aryl radical generation and also propagate the chain process.

Cobalt catalyzed C-P bond formation by cross-coupling of boronic acids with P(O)H compounds in presence of zinc

In our current work, we have reported the first cobalt-catalyzed cross-coupling of arylboronic acid with alkyl/aryl phosphites under mild conditions. The reaction was carried out in the presence of zinc powder as an additive and ter-pyridine as a ligand. The use of non-precious cobalt salt makes the protocol advantageous, as it is inexpensive and more abundant than the previously used methods where precious metal salts (Pd and Pt) were used. The reaction has a wide substrate scope and the products were obtained in good yields.

Nickel-Catalyzed Phosphorylation of Tosylates

Abstract: Four new bidentate phosphine ligands have been synthesized, characterized and evaluated in Ni-catalyzed C–P coupling reaction. The readily available and inexpensive highly active sulfonate Ni(cod)2-L8 catalyzes the reaction leading to

Controllable phosphorylation of thioesters: Selective synthesis of aryl and benzyl phosphoryl compounds

The controllable phosphorylations of thioesters were developed. When the reaction was catalyzed by a palladium catalyst, aryl or alkenyl phosphoryl compounds were generated through decarbonylative coupling, while the benzyl phosphoryl compounds were produced through deoxygenative coupling when the reaction was carried out in the presence of only a base.

Decarbonylative Phosphorylation of Carboxylic Acids via Redox-Neutral Palladium Catalysis

We describe the direct synthesis of organophosphorus compounds from ubiquitous aryl and vinyl carboxylic acids via decarbonylative palladium catalysis. The catalytic system shows excellent scope and tolerates a wide range of functional groups (>50 examples). The utility of this powerful methodology is highlighted in the late-stage derivatization directly exploiting the presence of the prevalent carboxylic acid functional group. DFT studies provided insight into the origin of high bond activation selectivity and P(O)-H isomerization pathway.

Direct Aryloxylation/Alkyloxylation of Dialkyl Phosphonates for the Synthesis of Mixed Phosphonates

A strategy for the direct functionalization strategy of inertial dialkyl phosphonates with hydroxy compounds to afford diverse mixed phosphonates with good yields and functional-group tolerance has been developed. Mechanistic investigations involving both NMR studies and DFT studies suggest that an unprecedented highly reactive PV species (phosphoryl pyridin-1-ium salt), a key intermediate for this new synthetic transformation, is generated in situ from dialkyl phosphonate in the presence of Tf2O/pyridine.

Visible-Light-Mediated Metal-Free Synthesis of Aryl Phosphonates: Synthetic and Mechanistic Investigations

This work describes a straightforward access to a large variety of aryl phosphonates by the simple combination of diaryliodonium salts with phosphites in the presence of a base and under visible-light illumination. The reaction proceeds smoothly, tolerates various functionalities, and was applied for the synthesis of pharmaceutically relevant compounds. Mechanistic investigations, including EPR, NMR, and DFT calculations, support the postulated reaction mechanism.

Avisible-light-promoted metal-free strategy towards arylphosphonates: Organic-dye-catalyzed phosphorylation of arylhydrazines with trialkylphosphites

A visible-light-induced metal-free catalytic system was developed for the synthesis of arylphosphonates starting from arylhydrazines and trialkylphosphites. By using the inexpensive eosin B as catalyst, sub-stoichiometric amounts of DABCO, and ambient air as oxidant, diverse arylphosphonates were obtained under visible-light irradiation. Notably, this catalytic system is suitable for gram-scale reaction by utilizing sunlight as an illumination source.