7670-94-2Relevant academic research and scientific papers
Selective hydrolysis of phosphorus(v) compounds to form organophosphorus monoacids
Ash, Jeffrey,Cordero, Paula,Huang, Hai,Kang, Jun Yong
, p. 6007 - 6014 (2021/07/21)
An azide and transition metal-free method for the synthesis of elusive phosphonic, phosphinic, and phosphoric monoacids has been developed. Inert pentavalent P(v)-compounds (phosphonate, phosphinate, and phosphate) are activated by triflate anhydride (Tf2O)/pyridine system to form a highly reactive phosphoryl pyridinium intermediate that undergoes nucleophilic substitution with H2O to selectively deprotect one alkoxy group and form organophosphorus monoacids.
Direct conversion of secondary phosphine oxides and h-phosphinates with [Di(acyloxy)iodo]benzenes to phosphinic and phosphonic amides
Hubacz, Anna,Makowiec, Slawomir
experimental part, p. 81 - 86 (2009/09/25)
The reaction of [di(acyloxy)iodo]- benzene with secondary phosphine oxides or H-phosphinates in the presence of primary or secondary amines allows one to obtain phosphinic or phosphonic acids amides in the one-pot process. We take advantage of the strong acylating system DAIB/R2P(O)H to phosphinylation of amines. However, the reaction mechanism is multipathway and causes yields of phosphinic or phosphonic acids amides to be moderate. When the concentration of amines is low, the intermolecular process plays a main role leading to the formation of carboxylic amides through mixed phosphoric-carboxylic anhydride, and also in the low concentration of amines, tetrahydrofuran effectively competes with the amines in the nucleophilic attack on the acylating intermediates.
Reactivity of diacyloxyiodobenzenes toward trivalent phosphorus nucleophiles
Makowiec, Slawomir,Rachon, Janusz
, p. 352 - 359 (2007/10/03)
The reaction of diacyloxyiodobenzenes and tetravalent phosphorus nucleophiles was investigated. It was established that both H-phosphonates and secondary phosphine oxides react with diacetoxyiodobenzene in alcohols in the presence of sodium alcoholates yi
The Selective Dealkylation of Mixed Esters of Phosphoric Acid and Phenylphosphonic Acid Using Cation Exchange Resin
Nitta, Yoshihiro,Arakawa, Yasushi
, p. 3121 - 3129 (2007/10/02)
Cation exchange resin (SO3H) is a highly selective dealkylation reagent for mixed esters of phosphorus oxyacids bearing primary and secondary alkyl groups.The desired products which were produced by dealkylation of the secondary alkyl group were obtained in high yields under anhydrous and mild conditions.Keywords - dealkylation; cation exchange resin; carbonium ion; phosphorus oxyacid ester; trialkyl phosphate; dialkyl phenylphosphonate; p-toluenesulfonic acid
