72615-50-0

Upstream product

• 57427-79-9 (Z)-4-(4-methylbenzylidene)-2-phenyloxazol-5(4H)-one 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 100-66-3 methoxybenzene 
• 82309-33-9 4-(4-methylbenzylidene)-2-phenyloxazol-5-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 105962-38-7 methyl Z-2-benzamido-3-p-methylphenyl-2-butanoate 
• 111016-43-4 4-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester 
• 111016-48-9 4-p-Tolyl-1H-pyrazole-3-carboxylic acid 
• 111016-46-7 4-(4-toyl)-1H-pyrazole 

Relevant academic research and scientific papers

One-pot process to Z-α-benzoylamino-acrylic acid methyl esters via potassium phosphate-catalyzed Erlenmeyer reaction

A practical and efficient two reaction sequence one-pot process for the synthesis of Z-α-benzoylamino-acrylic acid methyl esters was developed. The process involves a potassium phosphate-catalyzed Erlenmeyer reaction of aromatic aldehydes with hippuric acid followed by an oxazolone ring-opening methanolysis. This process afforded a good overall yield and an excellent product quality via a simple workup.

An usual behaviour of ethers in presence of azlactones under ultrasound irradiation to give esters

The phenomenon of ester formation from ethers and azlactones under sonolysis has been observed.

A new methodology for the synthesis of N-acylaminocinnamates

A new synthesis of biologically active N-protected amino acids (2) and amides (4) from 4-ylidene-5(4H)-oxazolones (1) is described.

Synthesis of Isomeric Methyl- and Dimethyl-Substituted 4-Benzylidene-2-phenyloxazolin-5-ones and Ring-Opened Derivatives

4-Benzylidene-2-phenyloxazolin-5-one and 15 mono- and dimethylated isomers as well as their ring-opened methyl ester and acid derivatives have been synthesized.Absorption spectroscopy indicates insignificant changes in the chromophore due to the methyl groups.